ALMOTRIPTAN
Synonym(s):3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate;PNU 180638
- CAS NO.：181183-52-8
- Empirical Formula: C21H31N3O7S
- Molecular Weight: 469.55
- MDL number: MFCD08067740
- EINECS: 815-382-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-10-31 16:47:27
What is ALMOTRIPTAN?
Description
Almotriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s = 12 and 13 nM, respectively, in a radioligand binding assay). It is selective for human 5-HT1B and 5-HT1D receptors over rat 5-HT1A and human 5-HT2A and 5-HT4 receptors (IC50s = 0.85, 25.1, and 140 μM, respectively). Almotriptan induces contractions in isolated canine saphenous veins (EC50 = 394 nM) but not isolated rabbit renal or mesenteric arteries. It increases carotid vascular resistance in anesthetized cats (ED100 = 11 μg/kg, i.v.) without increasing blood pressure or heart rate. Formulations containing almotriptan have been used in the treatment of migraine headaches.
The Uses of ALMOTRIPTAN
Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.
What are the applications of Application
Almotriptan Malate is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraines
Properties of ALMOTRIPTAN
| Melting point: | 170-172°C |
| storage temp. | 2-8°C |
| solubility | Basic Alcohol (Very Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| form | powder |
| color | white to beige |
Safety information for ALMOTRIPTAN
Computed Descriptors for ALMOTRIPTAN
Abamectin manufacturer
Varanous Labs Pvt Ltd
SMS Pharmaceuticals Ltd
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 3-NITRO-5-ACETYL IMINODIBENZYL 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THF 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE)Related products of tetrahydrofuran
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