8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Synonym(s):8-Br-cAMP;8-Bromo-cAMP, Na;Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 76939-46-3 - Calbiochem
- CAS NO.：76939-46-3
- Empirical Formula: C10H12BrN5NaO6P
- Molecular Weight: 432.1
- MDL number: MFCD00005844
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT?
Chemical properties
Off-white powder
The Uses of 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:
- to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture
- used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nuclei
- in superfusion medium for head kidneys stimulation
What are the applications of Application
8-Bromo-cAMP is a cell-permeable cyclic AMP (cAMP) analog that preferentially activates cAMP-dependent PKA.
General Description
8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide.
Biological Activity
Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset™ .
Biochem/physiol Actions
Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.
storage
-20°C (desiccate)
Properties of 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
| Melting point: | >264°C )dec._ |
| storage temp. | -20°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | off-white |
| Water Solubility | Soluble in water (100mM) |
| BRN | 7739743 |
| Stability: | Hygroscopic, Moisture Sensitive |
Safety information for 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
Adenosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt CAS 76939-46-3View Details
76939-46-3 -
8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt CAS 76939-46-3View Details
76939-46-3 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.