7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one
- CAS NO.:5307-99-3
- Empirical Formula: C7H6Cl2O
- Molecular Weight: 177.03
- MDL number: MFCD00013738
- EINECS: 226-165-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one?
Chemical properties
clear brown liquid
Synthesis
Under nitrogen protection, to a solution of dichloracetyl chloride (34 g, 0.23 mol) and cyclopentadiene(60 ml, 0.7 mol) in pentane (230 ml), heated to reflux in a three-necked flask with constant pressure funnel and condenser tube, was added dropwise via funnel triethylamine (24 g, 0.24 mol) in pentane (100 ml) with mechanical stirring during 4 hours, and a lot of white triethylamine hydrochloride was produced. After reflux for 2 hours, water (80 ml) was added to dissolve the triethylamine hydrochloride. The reaction mixture was extracted with pentane (2 × 60ml). The combined extracts were filtered and dried over anhydrous Na2SO4, and concentrated in vacuo to give brownish black oil. Fraction of reduced pressure distillation at 83~87 °C/400 Pa was collected to give 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one (2, 33.5 g) as a colorless oil.
Properties of 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one
Boiling point: | 58-64 °C (0.5 mmHg) |
Density | 1.44±0.1 g/cm3(Predicted) |
refractive index | 1.5150 |
Flash point: | 127-128°C/25mm |
storage temp. | Refrigerator (+4°C) |
color | Clear, dark orange |
BRN | 2045059 |
CAS DataBase Reference | 5307-99-3(CAS DataBase Reference) |
Safety information for 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one
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