5'-O-Dimethoxytrityl-deoxythymidine

Synonym(s):DMT-T

CAS NO.：40615-39-2
Empirical Formula: C31H32N2O7
Molecular Weight: 544.59
MDL number: MFCD00010113
EINECS: 255-003-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-08 17:00:29

5'-O-Dimethoxytrityl-deoxythymidine Structural

What is 5'-O-Dimethoxytrityl-deoxythymidine?

Chemical properties

White Powder

The Uses of 5'-O-Dimethoxytrityl-deoxythymidine

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.

General Description

5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.

Flammability and Explosibility

Not classified

Properties of 5'-O-Dimethoxytrityl-deoxythymidine

Melting point:	114-116 °C (subl.)(lit.)
Boiling point:	618.41°C (rough estimate)
Density	1.2483 (rough estimate)
vapor pressure	0Pa at 20℃
refractive index	7 ° (C=1, MeOH)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder
pka	9.55±0.10(Predicted)
color	White to off-white
Water Solubility	3mg/L at 20℃
BRN	599297
Stability:	Store in Freezer
CAS DataBase Reference	40615-39-2(CAS DataBase Reference)
EPA Substance Registry System	Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2)

Safety information for 5'-O-Dimethoxytrityl-deoxythymidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment.