5'-O-Dimethoxytrityl-deoxythymidine
Synonym(s):DMT-T
- CAS NO.:40615-39-2
- Empirical Formula: C31H32N2O7
- Molecular Weight: 544.59
- MDL number: MFCD00010113
- EINECS: 255-003-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-08 17:00:29
What is 5'-O-Dimethoxytrityl-deoxythymidine?
Chemical properties
White Powder
The Uses of 5'-O-Dimethoxytrityl-deoxythymidine
5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.
General Description
5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.
Flammability and Explosibility
Not classified
Properties of 5'-O-Dimethoxytrityl-deoxythymidine
Melting point: | 114-116 °C (subl.)(lit.) |
Boiling point: | 618.41°C (rough estimate) |
Density | 1.2483 (rough estimate) |
vapor pressure | 0Pa at 20℃ |
refractive index | 7 ° (C=1, MeOH) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Powder |
pka | 9.55±0.10(Predicted) |
color | White to off-white |
Water Solubility | 3mg/L at 20℃ |
BRN | 599297 |
Stability: | Store in Freezer |
CAS DataBase Reference | 40615-39-2(CAS DataBase Reference) |
EPA Substance Registry System | Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2) |
Safety information for 5'-O-Dimethoxytrityl-deoxythymidine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H413:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for 5'-O-Dimethoxytrityl-deoxythymidine
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product: 40615-39-2 98%
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