5'-O-Dimethoxytrityl-deoxythymidine
Synonym(s):DMT-T
- CAS NO.：40615-39-2
- Empirical Formula: C31H32N2O7
- Molecular Weight: 544.59
- MDL number: MFCD00010113
- EINECS: 255-003-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 5'-O-Dimethoxytrityl-deoxythymidine?
Chemical properties
White Powder
The Uses of 5'-O-Dimethoxytrityl-deoxythymidine
5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.
General Description
5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.
Flammability and Explosibility
Not classified
Properties of 5'-O-Dimethoxytrityl-deoxythymidine
| Melting point: | 114-116 °C (subl.)(lit.) |
| Boiling point: | 618.41°C (rough estimate) |
| Density | 1.2483 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 7 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 9.55±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | 3mg/L at 20℃ |
| BRN | 599297 |
| Stability: | Store in Freezer |
| CAS DataBase Reference | 40615-39-2(CAS DataBase Reference) |
| EPA Substance Registry System | Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2) |
Safety information for 5'-O-Dimethoxytrityl-deoxythymidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for 5'-O-Dimethoxytrityl-deoxythymidine
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