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HomeProduct name list5'-O-Dimethoxytrityl-deoxythymidine

5'-O-Dimethoxytrityl-deoxythymidine

Synonym(s):DMT-T

  • CAS NO.:40615-39-2
  • Empirical Formula: C31H32N2O7
  • Molecular Weight: 544.59
  • MDL number: MFCD00010113
  • EINECS: 255-003-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-11-08 17:00:29
5'-O-Dimethoxytrityl-deoxythymidine Structural

What is 5'-O-Dimethoxytrityl-deoxythymidine?

Chemical properties

White Powder

The Uses of 5'-O-Dimethoxytrityl-deoxythymidine

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.

General Description

5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.

Flammability and Explosibility

Not classified

Properties of 5'-O-Dimethoxytrityl-deoxythymidine

Melting point: 114-116 °C (subl.)(lit.)
Boiling point: 618.41°C (rough estimate)
Density  1.2483 (rough estimate)
vapor pressure  0Pa at 20℃
refractive index  7 ° (C=1, MeOH)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Powder
pka 9.55±0.10(Predicted)
color  White to off-white
Water Solubility  3mg/L at 20℃
BRN  599297
Stability: Store in Freezer
CAS DataBase Reference 40615-39-2(CAS DataBase Reference)
EPA Substance Registry System Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2)

Safety information for 5'-O-Dimethoxytrityl-deoxythymidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.

Computed Descriptors for 5'-O-Dimethoxytrityl-deoxythymidine

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