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HomeProduct name list5-Chloro-1,3-dimethoxybenzene

5-Chloro-1,3-dimethoxybenzene

  • CAS NO.:7051-16-3
  • Empirical Formula: C8H9ClO2
  • Molecular Weight: 172.61
  • MDL number: MFCD00008382
  • EINECS: 230-330-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
5-Chloro-1,3-dimethoxybenzene Structural

What is 5-Chloro-1,3-dimethoxybenzene?

Description

5-Chloroesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.

Chemical properties

White to yellow or pink crystalline powder

The Uses of 5-Chloro-1,3-dimethoxybenzene

5-Chloro-1,3-dimethoxybenzene was used in the regioselective synthesis of TMC-264, tricyclic structure having chloro-1H-dibenzo[b,d]pyran-4,6-dione skeleton.

What are the applications of Application

5-Chlororesorcinol dimethyl ether is A synthetic intermediate useful for pharmaceutical synthesis

General Description

5-Chloro-1,3-dimethoxybenzene participates in Suzuki-Miyaura cross-coupling reactions of aryl- and heteroaryl chlorides with potassium cyclobutyltrifluoroborate.

Properties of 5-Chloro-1,3-dimethoxybenzene

Melting point: 34-36 °C (lit.)
Boiling point: 82-83°C 0,6mm
Density  1.1910 (rough estimate)
refractive index  1.5100 (estimate)
Flash point: 234 °F
storage temp.  Sealed in dry,Room Temperature
solubility  almost transparency in Methanol
form  Crystalline Powder
color  White to yellow or pink
BRN  2327304
CAS DataBase Reference 7051-16-3(CAS DataBase Reference)

Safety information for 5-Chloro-1,3-dimethoxybenzene

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 5-Chloro-1,3-dimethoxybenzene

InChIKey WQHNWJBSROXROL-UHFFFAOYSA-N

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