4,4'-DIMETHOXYBENZHYDROL

Synonym(s):Bis(4-methoxyphenyl)carbinol

CAS NO.：728-87-0
Empirical Formula: C15H16O3
Molecular Weight: 244.29
MDL number: MFCD00008410
EINECS: 211-975-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-08-17 18:11:45

What is 4,4'-DIMETHOXYBENZHYDROL?

Chemical properties

white to off-white crystalline powder

The Uses of 4,4'-DIMETHOXYBENZHYDROL

4,4?-Dimethoxybenzhydrol was used to study the kinetics and mechanism of oxidation of substituted benzhydrols to corresponding benzophenones in the presence of Hg(OAc)2 by N-bromosuccinimide. It is useful in the protection of glutamine and asparagine residues in peptide synthesis, reagent for the N-protection of amides.

General Description

4,4′-Dimethoxybenzhydrol causes N-alkylation of amides, lactams, carbamates, ureas and anilines in acetic acid during H₂SO₄ catalysis.

Properties of 4,4'-DIMETHOXYBENZHYDROL

Melting point:	67-70 °C(lit.)
Boiling point:	347.2°C (rough estimate)
Density	1.1263 (rough estimate)
refractive index	1.5570 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	methanol: 0.1 g/mL, clear
pka	13.68±0.20(Predicted)
form	Solid
color	White
Water Solubility	Soluble in water (0.44 g/L @ 25°C), methanol (0.1 g/mL).
BRN	748532
CAS DataBase Reference	728-87-0(CAS DataBase Reference)