2',7'-DICHLOROFLUORESCIN DIACETATE
Synonym(s):DCFHDA;Dcfh-DA;Diacetyldichlorofluorescein
- CAS NO.：2044-85-1
- Empirical Formula: C24H14Cl2O7
- Molecular Weight: 485.27
- MDL number: MFCD00037501
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is 2',7'-DICHLOROFLUORESCIN DIACETATE?
Chemical properties
off-white powder or crystals
The Uses of 2',7'-DICHLOROFLUORESCIN DIACETATE
2′,7′-Dichlorofluorescein diacetate may be used as a superior gas phase alternative to underivatized fluorescein and as a component/substrate of the 2′,7′-dichlorofluorescein diacetate assay to quantitate reactive oxygen species (ROS).
The Uses of 2',7'-DICHLOROFLUORESCIN DIACETATE
Cell permeable, sensitive indicator of peroxynitrite formation. After hydrolysis of the diacetate groups by cytosolic esterases or base-catalyzed cleavage of the diacetate groups, DCDHF is oxidized by peroxynitrite yielding the highly fluorescent product
What are the applications of Application
2′,7′-Dichlorofluorescein diacetate is a cell-permeable fluorogenic ROS probe
Properties of 2',7'-DICHLOROFLUORESCIN DIACETATE
| Melting point: | 232-234 °C(lit.) |
| Boiling point: | 657.9±55.0 °C(Predicted) |
| Density | 1.59±0.1 g/cm3(Predicted) |
| Flash point: | >109℃ |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | Powder or Crystals |
| color | Colorless to off-white |
| BRN | 68488 |
Safety information for 2',7'-DICHLOROFLUORESCIN DIACETATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2',7'-DICHLOROFLUORESCIN DIACETATE
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