2',7'-DICHLOROFLUORESCIN DIACETATE

Synonym(s):DCFHDA;Dcfh-DA;Diacetyldichlorofluorescein

CAS NO.：2044-85-1
Empirical Formula: C24H14Cl2O7
Molecular Weight: 485.27
MDL number: MFCD00037501
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

2',7'-DICHLOROFLUORESCIN DIACETATE Structural

What is 2',7'-DICHLOROFLUORESCIN DIACETATE?

Chemical properties

off-white powder or crystals

The Uses of 2',7'-DICHLOROFLUORESCIN DIACETATE

Cell permeable, sensitive indicator of peroxynitrite formation. After hydrolysis of the diacetate groups by cytosolic esterases or base-catalyzed cleavage of the diacetate groups, DCDHF is oxidized by peroxynitrite yielding the highly fluorescent product

The Uses of 2',7'-DICHLOROFLUORESCIN DIACETATE

2′,7′-Dichlorofluorescein diacetate may be used as a superior gas phase alternative to underivatized fluorescein and as a component/substrate of the 2′,7′-dichlorofluorescein diacetate assay to quantitate reactive oxygen species (ROS).

What are the applications of Application

2′,7′-Dichlorofluorescein diacetate is a cell-permeable fluorogenic ROS probe

Properties of 2',7'-DICHLOROFLUORESCIN DIACETATE

Melting point:	232-234 °C(lit.)
Boiling point:	657.9±55.0 °C(Predicted)
Density	1.59±0.1 g/cm3(Predicted)
Flash point:	>109℃
storage temp.	2-8°C
solubility	DMSO: soluble
form	Powder or Crystals
color	Colorless to off-white
BRN	68488

Safety information for 2',7'-DICHLOROFLUORESCIN DIACETATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.