4,4'-Dimethoxybenzophenone

CAS NO.：90-96-0
Empirical Formula: C15H14O3
Molecular Weight: 242.27
MDL number: MFCD00008404
EINECS: 202-028-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is 4,4'-Dimethoxybenzophenone?

Chemical properties

white to light yellow crystal powder

The Uses of 4,4'-Dimethoxybenzophenone

4,4'-Dimethoxybenzophenone is used in the organic synthesis. It also acts as a pharmaceutical intermediate. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Preparation

btained by photocatalytic oxidation of 4,4–′-dimethoxybenzhydrol (m.p. 69–71°) catalyzed by H3PW12O40/SiO2 in acetonitrile under oxygen atmosphere at r.t. for 1 h (90%).

Synthesis Reference(s)

Journal of the American Chemical Society, 91, p. 3037, 1969 DOI: 10.1021/ja01039a036
Tetrahedron Letters, 30, p. 1277, 1989 DOI: 10.1016/S0040-4039(00)72735-3

General Description

Photoreactivity of 4,4′-dimethoxybenzophenone with 2-aminobenzimidazole has been examined. It is an ultraviolet absorbing additive in plastic products.

Purification Methods

Crystallise the ketone from absolute EtOH, aqueous EtOH or EtOH/AcOH. The 2,4-dinitrophenylhydrazone has m 199-200o. [Beilstein 8 H 317, 8 I 641, 8 II 355, 8 III 2649, 8 IV 2453.]

Properties of 4,4'-Dimethoxybenzophenone

Melting point:	141-143 °C (lit.)
Boiling point:	200 °C17 mm Hg(lit.)
Density	1.1515 (rough estimate)
refractive index	1.5570 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Powder
color	Slightly beige to yellow
Water Solubility	It is insoluble in water, soluble in ethanol.
BRN	1878026
CAS DataBase Reference	90-96-0(CAS DataBase Reference)
NIST Chemistry Reference	P,p'-dimethoxybenzophenone(90-96-0)

Safety information for 4,4'-Dimethoxybenzophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.