4-Methoxypyridine
- CAS NO.:620-08-6
- Empirical Formula: C6H7NO
- Molecular Weight: 109.13
- MDL number: MFCD00674049
- EINECS: 210-624-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-05 17:10:12
What is 4-Methoxypyridine?
Chemical properties
clear colorless to slightly yellow liquid
The Uses of 4-Methoxypyridine
4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.
The Uses of 4-Methoxypyridine
4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.
General Description
4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.
Properties of 4-Methoxypyridine
Melting point: | 4 °C |
Boiling point: | 108-111 °C/65 mmHg (lit.) |
Density | 1.075 g/mL at 25 °C (lit.) |
refractive index | 1.518-1.522 |
Flash point: | 74 °C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Liquid |
pka | 6.58(at 25℃) |
Specific Gravity | 1.075 |
color | Clear colorless to slightly yellow |
BRN | 108211 |
CAS DataBase Reference | 620-08-6(CAS DataBase Reference) |
NIST Chemistry Reference | Pyridine, 4-methoxy-(620-08-6) |
Safety information for 4-Methoxypyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Methoxypyridine
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