4-Methoxybenzylchloride
Synonym(s):4-(Chloromethyl)anisole
- CAS NO.：824-94-2
- Empirical Formula: C8H9ClO
- Molecular Weight: 156.61
- MDL number: MFCD00000915
- EINECS: 212-540-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is 4-Methoxybenzylchloride?
Chemical properties
Colorless liquid
The Uses of 4-Methoxybenzylchloride
O/N protecting group reagent which can be mildly oxidatively cleaved, e.g., with ceric ammonium nitrate.
What are the applications of Application
4-Methoxybenzyl chloride is a Suzuki cross-coupling reagent
Synthesis Reference(s)
Journal of Medicinal Chemistry, 20, p. 190, 1977 DOI: 10.1021/jm00212a002
The Journal of Organic Chemistry, 53, p. 3634, 1988 DOI: 10.1021/jo00250a048
General Description
4-Methoxybenzyl chloride undergoes mild oxidative claevage with ceric ammonium nitrate.
Purification Methods
Purify 4-anisyl chloride by fractional distillation under vacuum, and the middle fraction is redistilled at 10-6 mm at room temperature by intermittent cooling of the receiver in liquid N2, and the middle fraction is collected. [Mohammed & Kosower J Am Chem Soc 93 2709 1971, Beilstein 6 IV 2137.]
Properties of 4-Methoxybenzylchloride
| Melting point: | −1 °C(lit.) |
| Boiling point: | 117-118 °C14 mm Hg(lit.) |
| Density | 1.155 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 229 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Water Solubility | slowly decomposes |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 824-94-2(CAS DataBase Reference) |
| NIST Chemistry Reference | «alpha»-Chloro-4-methoxytoluene(824-94-2) |
Safety information for 4-Methoxybenzylchloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H290:Corrosive to Metals H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P234:Keep only in original container. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P390:Absorb spillage to prevent material damage. P405:Store locked up. P406:Store in corrosive resistant/… container with a resistant inner liner. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Methoxybenzylchloride
| InChIKey | MOHYOXXOKFQHDC-UHFFFAOYSA-N |
4-Methoxybenzylchloride manufacturer
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
2Y
Phone:+91-9966658228
Whatsapp: +91- 9966658228
product: 824-94-2 4-Methoxy Benzyl chloride, contains 1% potassium carbonate as stabilizer, 95% 99%
SOLFYN INTERNATIONAL LLP
1Y
Phone:+91-9321772608
Whatsapp: +91 9321772608
product: 824-94-2 4-METHOXYBENZYL CHLORIDE 99%
Erevna Pharma Private Limited
1Y
Phone:+919884394900
Whatsapp: +91-9962143988
product: 824-94-2 4-Methoxybenzyl chloride 98%
Medchem Labs
1Y
Phone:+91-7288889555
Whatsapp: +91-7288889555
product: 4-Methoxybenzyl chloride 824-94-2 98%
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 824-94-2 4-Methoxybenzyl chloride 98%
Dr R R Organics
1Y
Phone:+91-9666306440
Whatsapp: +91-9666306440
product: 4-Methoxybenzyl chloride 98%
Innovative Labs
1Y
Phone:+91-9885794886
Whatsapp: +91-9885794886
product: 4-Methoxybenzyl chloride 824-94-2 98%
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
824-94-2 4-Methoxybenzyl Chloride 98%View Details
824-94-2 -
4-Methoxybenzyl chloride 824-94-2 98%View Details
824-94-2 -
824-94-2 4-Methoxybenzyl chloride 98%View Details
824-94-2 -
824-94-2 4-METHOXYBENZYL CHLORIDE 99%View Details
824-94-2 -
4-Methoxybenzyl chloride 98%View Details
824-94-2 -
824-94-2 4-Methoxybenzyl chloride 98%View Details
824-94-2 -
4-Methoxybenzyl Chloride (stabilized with Amylene) CAS 824-94-2View Details
824-94-2 -
4-Methoxybenzyl chloride CAS 824-94-2View Details
824-94-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.