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HomeProduct name list4-(Dimethylamino)benzophenone

4-(Dimethylamino)benzophenone

Synonym(s):p -Benzoyl-N ,N -dimethylaniline;4-Benzoyl-N ,N -dimethylaniline

  • CAS NO.:530-44-9
  • Empirical Formula: C15H15NO
  • Molecular Weight: 225.29
  • MDL number: MFCD00008311
  • EINECS: 208-478-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-27 16:27:43
4-(Dimethylamino)benzophenone Structural

What is 4-(Dimethylamino)benzophenone?

Chemical properties

YELLOW CRYSTALLINE POWDER OR CRYSTALS

The Uses of 4-(Dimethylamino)benzophenone

4-(Dimethylamino)benzophenone is an important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Synthesis Reference(s)

Synthesis, p. 544, 1986 DOI: 10.1055/s-1986-31696
Tetrahedron Letters, 34, p. 7595, 1993 DOI: 10.1016/S0040-4039(00)60409-4

Purification Methods

Crystallise the pale green p-dimethylaminobenzophenone from EtOH. Dissolve 100g in 600mL of boiling EtOH, add 5g of charcoal, cool, isolate the solid by centrifugation and similarly wash the pale crystals with ice-cold EtOH. When filtered by suction, EtOH solution remains on the crystals and turns deep green in air. Dry it in a vacuum and store it in the dark. The hydrazone has m 128-130o and forms a ketyl with potassium. [Hurd & Webb Org Synth Coll Vol I 217 1941, Beilstein 14 H 82, 14 I 288, 14 III 218, 14 IV 248.]

Properties of 4-(Dimethylamino)benzophenone

Melting point: 88-90 °C(lit.)
Boiling point: 250 °C / 15mmHg
Density  1.0463 (rough estimate)
refractive index  1.5200 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  powder to crystal
pka 2.12±0.12(Predicted)
color  White to Light yellow to Green
Water Solubility  insoluble
Merck  14,3233
CAS DataBase Reference 530-44-9(CAS DataBase Reference)
NIST Chemistry Reference Methanone, [4-(dimethylamino)phenyl]phenyl-(530-44-9)
EPA Substance Registry System Methanone, [4-(dimethylamino)phenyl]phenyl- (530-44-9)

Safety information for 4-(Dimethylamino)benzophenone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-(Dimethylamino)benzophenone

InChIKey BEUGBYXJXMVRFO-UHFFFAOYSA-N

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