4-Chlorobenzophenone

Chemical properties

White to off-white powder

The Uses of 4-Chlorobenzophenone

4-Chlorobenzophenone is a versatile building block in chemical synthesis, particularly for the preparation of a wide range of functionalized Coumarin derivatives.

The Uses of 4-Chlorobenzophenone

UV curing type coating, printing ink, medical and pesticide intermediate

Definition

ChEBI: 4-chlorobenzophenone is a member of benzophenones. It is a known transformation product of 1-[(4-Chlorophenyl)phenylmethyl]piperazine, Cetirizine, Cetirizine N-oxide, Chlorcyclizine, and Meclozine.

Synthesis Reference(s)

Tetrahedron Letters, 40, p. 3109, 1999 DOI: 10.1016/S0040-4039(99)00476-1

Toxicology

May cause SENSITISATION by skin contact. Irritating to eyes, respiratory system and skin. The material has NOT been classified as "harmful by ingestion".
This material can cause eye irritation and damage in some persons.
The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. 
Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled

Purification Methods

Recrystallise it from EtOH. [Wagner et al. J Am Chem Soc 108 7727 1986, Beilstein 7 H 419, 7 I 227, 7 II 359, 7 III 2072, 7 IV 1375.]