Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

Synonym(s):5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid;HMBS;Sulisobenzone

  • CAS NO.:4065-45-6
  • Empirical Formula: C14H12O6S
  • Molecular Weight: 308.31
  • MDL number: MFCD00024962
  • EINECS: 223-772-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Structural

What is 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid?

Chemical properties

white to yellowish powder

Originator

Uval,Dome,US,1965

The Uses of 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid is a commonly used, FDA approved sunscreen chemical with uVA-absorbing properties and an approved usage level of 5 to 10 percent. It protects a formulation from the effects of uV-light exposure.

The Uses of 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

Ultraviolet absorber for leather and textile fibers; in cosmetics and shampoos.

The Uses of 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

sulisobenzone is the drug name for benzophenone-4, a sunscreen chemical.

Definition

ChEBI: Sulisobenzone is a member of benzophenones.

Manufacturing Process

663 g of dichloroethane and 74.6 g 2-hydroxy-4-methoxybenzophenone were charged into a 3-neck flask equipped with stirrer, thermometer, reflux condenser and dropping funnel and a heating mantle. The solution was heated to the reflux temperature (85°C to 86°C) and was dehydrated by distilling off 66.5 g 1,2-dichloroethane. While maintaining at reflux, 30 g chlorosulfonic acid was added slowly over a period of about two hours. The rate of addition was regulated by the speed of evolution of the HCl. After all the chlorosulfonic acid was added, the charge was still maintained at reflux for an additional 15 minutes to remove traces of HCl. It was then cooled to 5°C and filtered. The filter cake was washed with 500 g cold 1,2-dichloroethane and dried. 98 g of product were obtained.

brand name

Sungard (Bayer).

Therapeutic Function

Sunscreen agent

General Description

Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.

Flammability and Explosibility

Non flammable

Contact allergens

BZP-4 is widely used in cosmetics, particularly shampoos and hair products. Cross-reactivity is rarely expected in patients photoallergic to ketoprofen.

Properties of 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

Melting point: 170 °C
Boiling point: 0°C
Density  1.4574 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.5300 (estimate)
Flash point: 0°C
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka -0.70±0.50(Predicted)
form  neat
form  Solid
color  White to Off-White
Water Solubility  300.92g/L at 25℃
Merck  14,8983
BRN  2889165
CAS DataBase Reference 4065-45-6(CAS DataBase Reference)
EPA Substance Registry System Sulisobenzone (4065-45-6)

Safety information for 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

Computed Descriptors for 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

InChIKey CXVGEDCSTKKODG-UHFFFAOYSA-N

Related products of tetrahydrofuran

You may like

  • 4065-45-6 BENZOPHENONE  4 99%
    4065-45-6 BENZOPHENONE 4 99%
    4065-45-6
    View Details
  • 4065-45-6 99%
    4065-45-6 99%
    4065-45-6
    View Details
  • 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid hydrate CAS 4065-45-6
    2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid hydrate CAS 4065-45-6
    4065-45-6
    View Details
  • 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, ≥97% CAS 4065-45-6
    5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, ≥97% CAS 4065-45-6
    4065-45-6
    View Details
  • 2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid (contains ca. 10% Isopropyl Alcohol) CAS 4065-45-6
    2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid (contains ca. 10% Isopropyl Alcohol) CAS 4065-45-6
    4065-45-6
    View Details
  • Sulisobenzone 4065-45-6 99%
    Sulisobenzone 4065-45-6 99%
    4065-45-6
    View Details
  • Sulisobenzone >98% (HPLC) CAS 4065-45-6
    Sulisobenzone >98% (HPLC) CAS 4065-45-6
    4065-45-6
    View Details
  • 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid CAS 4065-45-6
    5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid CAS 4065-45-6
    4065-45-6
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.