4-Deoxypyridoxine hydrochloride
- CAS NO.:148-51-6
- Empirical Formula: C8H12ClNO2
- Molecular Weight: 189.64
- MDL number: MFCD00051296
- EINECS: 205-714-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:18
What is 4-Deoxypyridoxine hydrochloride?
Description
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.
Chemical properties
Solid
The Uses of 4-Deoxypyridoxine hydrochloride
4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease.
What are the applications of Application
4-Deoxypyridoxine hydrochloride is a vitamin B6 antagonist
Properties of 4-Deoxypyridoxine hydrochloride
Melting point: | 274°C(dec.)(lit.) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
form | neat |
form | Solid |
color | White to Pale Red |
Stability: | Hygroscopic |
CAS DataBase Reference | 148-51-6(CAS DataBase Reference) |
Safety information for 4-Deoxypyridoxine hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Deoxypyridoxine hydrochloride
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