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HomeProduct name list4-Deoxypyridoxine hydrochloride

4-Deoxypyridoxine hydrochloride

  • CAS NO.:148-51-6
  • Empirical Formula: C8H12ClNO2
  • Molecular Weight: 189.64
  • MDL number: MFCD00051296
  • EINECS: 205-714-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 08:55:18
4-Deoxypyridoxine hydrochloride Structural

What is 4-Deoxypyridoxine hydrochloride?

Description

4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.

Chemical properties

Solid

The Uses of 4-Deoxypyridoxine hydrochloride

4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease.

What are the applications of Application

4-Deoxypyridoxine hydrochloride is a vitamin B6 antagonist

Properties of 4-Deoxypyridoxine hydrochloride

Melting point: 274°C(dec.)(lit.)
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form  neat
form  Solid
color  White to Pale Red
Stability: Hygroscopic
CAS DataBase Reference 148-51-6(CAS DataBase Reference)

Safety information for 4-Deoxypyridoxine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-Deoxypyridoxine hydrochloride

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