4-Chlorophenylacetic acid

CAS NO.：1878-66-6
Empirical Formula: C8H7ClO2
Molecular Weight: 170.59
MDL number: MFCD00004344
EINECS: 217-521-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 4-Chlorophenylacetic acid?

Chemical properties

white to cream colored powder

The Uses of 4-Chlorophenylacetic acid

4-Chlorophenylacetic acid was used to study the mechanism of aerobic degradation of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane by Ralstonia eutropha A5.

The Uses of 4-Chlorophenylacetic acid

4-Chlorophenylacetic Acid is a chlorinated phenyl acetic acid that is an antitumor differentiation inducer and may be an effective therapeutic agent in neuroblastoma therapy. 4-Chlorophenylacetic Acid shows plant growth-regulating activity.

Definition

ChEBI: A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-chlorophenyl group.

General Description

4-Chlorophenylacetic acid possess anticancer properties. It is a novel therapeutic agent which can be useful in prevention or treatment of estrogen-sensitive breast cancer. It acts as carbon and energy supplement and is degraded by Pseudomonas sp. strain CBS3.

Purification Methods

Purify it as for 3-chlorophenylacetic acid. [Beilstein 9 III 2263, 9 IV 1674.]

Properties of 4-Chlorophenylacetic acid

Melting point:	102-105 °C(lit.)
Boiling point:	241.44°C (rough estimate)
Density	1.2315 (rough estimate)
refractive index	1.5660 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	ethanol: soluble100mg/mL, clear, faintly yellow
form	Powder
pka	4.19(at 25℃)
color	White to cream
PH	2.5-3 (100g/l, H2O, 20℃)suspension
BRN	1072816
InChI	InChI=1S/C8H7ClO2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2,(H,10,11)
CAS DataBase Reference	1878-66-6(CAS DataBase Reference)
NIST Chemistry Reference	Acetic acid, p-chlorophenyl-(1878-66-6)
EPA Substance Registry System	p-Chlorophenylacetic acid (1878-66-6)

Safety information for 4-Chlorophenylacetic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.