4'-Chloroacetophenone

CAS NO.：99-91-2
Empirical Formula: C8H7ClO
Molecular Weight: 154.59
MDL number: MFCD00000624
EINECS: 202-800-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 4'-Chloroacetophenone?

Chemical properties

clear colourless to yellowish liquid after melting

The Uses of 4'-Chloroacetophenone

Chloroacetophenone is used as a tear gas for riot control and as a kind of chemical mace against small groups or individuals

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 2568, 1979 DOI: 10.1021/jo01328a051
Tetrahedron Letters, 42, p. 265, 2001 DOI: 10.1016/S0040-4039(00)01935-3
Synthetic Communications, 25, p. 2261, 1995 DOI: 10.1080/00397919508011781

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. A powerful irritant and lachrymator. Human systemic effects by inhalation: lachrymation and unspecified effects on the eye and sense of smell. Combustible when exposed to heat or flame. To fight fire, use water, foam, alcohol foam, dry chemical. When heated to decomposition or on contact with water or steam it emits toxic fumes of Cl-

Properties of 4'-Chloroacetophenone

Melting point:	14-18 °C (lit.)
Boiling point:	232 °C (lit.)
Density	1.192 g/mL at 25 °C (lit.)
vapor pressure	8 mm Hg ( 90 °C)
refractive index	n20/D 1.554(lit.)
Flash point:	194 °F
storage temp.	Sealed in dry,Room Temperature
solubility	111mg/l (slow decomposition)
form	Liquid After Melting
color	Clear colorless to yellow
Odor	at 100.00 %. sweet mild acetophenone hay
Water Solubility	111 mg/L (25 ºC)
Merck	14,2116
BRN	386014
CAS DataBase Reference	99-91-2(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-(4-chlorophenyl)-(99-91-2)
EPA Substance Registry System	4'-Chloroacetophenone (99-91-2)

Safety information for 4'-Chloroacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.