4-Chlorophenethylamine

Synonym(s):4-Chlorophenethylamine

CAS NO.：156-41-2
Empirical Formula: C8H10ClN
Molecular Weight: 155.62
MDL number: MFCD00008191
EINECS: 205-853-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 15:53:33

What is 4-Chlorophenethylamine?

Chemical properties

Dark Solid

The Uses of 4-Chlorophenethylamine

2-(4-Chlorophenyl)ethylamine has been used as a reactant in the preparation of isoalloxazine derivatives as cholinesterase inhibitors with a potential use in Alzheimer therapy.

Description

4-Chlorophenethylamine(CPA) is a synthetic serotonergic amine that has inhibitory activities. It is able to bind with the 5-HT receptor, which is also known as the serotonin receptor. CPA has been shown to be an anticancer compound and can be used in experimental solubility studies. This drug binds to brain cells, but does not affect their viability.

Chemical reactions

4-Chlorophenethylamine(CPA) hydrolyzes in the presence of hydrochloric acid or hydrogen chloride to produce 2-(4-chlorophenyl)ethanol (CPE). The reaction of CPA with serotonin produces 4-chloroamphetamine (PCA), which is a stimulant drug.

Properties of 4-Chlorophenethylamine

Boiling point:	60-65 °C0.1 mm Hg(lit.)
Density	1.112 g/mL at 25 °C(lit.)
refractive index	n20/D 1.548(lit.)
Flash point:	223 °F
storage temp.	Store Cold
form	Liquid
pka	9.72±0.10(Predicted)
Specific Gravity	1.12
color	Clear colorless to yellow
BRN	508247
CAS DataBase Reference	156-41-2(CAS DataBase Reference)

Safety information for 4-Chlorophenethylamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.