4-Aminobenzamidine dihydrochloride
Synonym(s):p-Aminobenzimidamide dihydrochloride
- CAS NO.：2498-50-2
- Empirical Formula: C7H11Cl2N3
- Molecular Weight: 208.09
- MDL number: MFCD00013001
- EINECS: 219-692-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is 4-Aminobenzamidine dihydrochloride?
Chemical properties
white to yellowish fine crystalline powder
The Uses of 4-Aminobenzamidine dihydrochloride
4-Aminobenzamidine dihydrochloride is a synthetic diamidine derivative that acts as a urokinase inhibitor as well as trypsin inhibitor. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes.
What are the applications of Application
4-Aminobenzamidine dihydrochloride can be used to synthesize:
Orally active fibrinogen receptor antagonists based on benzamidines.
Benzamidine derivatives that are selective and potent serine protease inhibitors.
Novel pyrrolo [3,2-c] quinolines that are structural analogs of topoisomerase inhibitors such as coralyne and fagaronine.
Synthesis of a selective inhibitor of PRMT1 (SKLB-639)
Preparation
4-Aminobenzamididine dihydrochloride is obtained by cyanation, addition, amination and reduction of 4-nitrobenzoic acid.
Definition
ChEBI: P-Aminobenzamidine dihydrochloride is an organic molecular entity.
Properties of 4-Aminobenzamidine dihydrochloride
| Melting point: | >300 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Water |
| form | Fine Crystalline Powder |
| color | White to yellow |
| Sensitive | Hygroscopic |
| BRN | 3692927 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 2498-50-2(CAS DataBase Reference) |
Safety information for 4-Aminobenzamidine dihydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Aminobenzamidine dihydrochloride
| InChIKey | GHEHNICLPWTXJC-UHFFFAOYSA-N |
4-Aminobenzamidine dihydrochloride manufacturer
Vedanta Biosciences
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Phone:+91-9494438455
Whatsapp: +91 9494438455
product: 4-Aminobenzamidine dihydrochloride 98%
Rui Laboratories Pvt Ltd
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Phone:+91-9676323459
Whatsapp: +91-9676323459
product: 4-Aminobenzamidine dihydrochloride 2498-50-2 99%
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