4-Aminobenzoic acid
Synonym(s):4-Aminobenzoic acid;PABA;para-Aminobenzoic acid;Vitamin Bx;Vitamin H1
- CAS NO.:150-13-0
- Empirical Formula: C7H7NO2
- Molecular Weight: 137.14
- MDL number: MFCD00007894
- EINECS: 205-753-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-11 20:10:50
What is 4-Aminobenzoic acid?
Description
4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the number 4 carbon in the benzene ring is also known as the para position) is an organic compound with the formula H2NC6H4CO2H. PABA is a white solid, although commercial samples can appear gray. It is slightly soluble in water. It consists of a benzene ring substituted with amino and a carboxyl groups. The compound occurs naturally. The potassium salt is used as a drug against fibrotic skin disorders, such as Peyronie's disease, under the trade name Potaba. PABA is also occasionally used in pill form by sufferers of irritable bowel syndrome to treat its associated gastrointestinal symptoms, and in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels.
The Uses of 4-Aminobenzoic acid
4-aminobenzoic acid is an aminobenzoic acid isomer that combines with pteridine and glutamic acid to folic acid. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in sunscreens. Also it is used as a component of some medicines e.g analgesic or anesthetic preparations sunscreen agents and bentiromide.
Background
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Metabolism
Not Available
Properties of 4-Aminobenzoic acid
Melting point: | 187-189 °C(lit.) |
Boiling point: | 251.96°C (rough estimate) |
Density | 1.374 g/mL at 25 °C(lit.) |
Flash point: | 250 °C |
storage temp. | 2-8°C |
solubility | 95% ethanol: soluble5%, clear to slightly hazy, colorless to yellow |
form | Crystalline Powder |
color | White to light yellow |
Odor | Odorless |
Water Solubility | 4.7 g/L (20 ºC) |
Sensitive | Air & Light Sensitive |
Safety information for 4-Aminobenzoic acid
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Aminobenzoic acid
InChIKey | ALYNCZNDIQEVRV-UHFFFAOYSA-N |
Abamectin manufacturer
SAGAR LIFE SCIENCES PVT LTD
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Shree Ganesh Dye Chem
SURYA LIFE SCIENCES LIMITED
Sarex Overseas
Arown Pharma
PARAGON FINE AND SPECIALITY CHEMICAL PVT LTD
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