4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
- CAS NO.:694499-26-8
- Empirical Formula: C13H18F3N3
- Molecular Weight: 273.3
- MDL number: MFCD09909924
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-25 20:17:06
What is 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline?
The Uses of 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.
Synthesis
4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline Into a solution 4-methyl-1-(4-nitro-2-(trifluoromethyl)benzyl)piperazine (1.5 g, 5 mmol) in MeOH (250 mL) was added Raney Nickel (0.15 g, 10 wt %). The suspension was stirred under hydrogen atmosphere (50 psi) for 24 hrs and monitored by TLC. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to yield the desired product (1.36 g, 100%). 1H NMR (300 MHz, CDCl3) |?: 7.43-7.46 (1H, d, J=9.0 Hz), 6.91 (1H, s), 6.77-6.80 (1H, d J=9.0 Hz), 3.77 (2H, s), 3.54 (2H, s), 2.53 (8H, brs), 2.34 (3H, s).
storage
Store long-term at 2-8°C.
Properties of 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
Boiling point: | 329.1±42.0 °C(Predicted) |
Density | 1.227 |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
pka | 7.55±0.10(Predicted) |
InChI | InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3 |
Safety information for 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
InChIKey | ZMWAZMYBMAAMAW-UHFFFAOYSA-N |
SMILES | C1(N)=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1 |
Abamectin manufacturer
Neochemsys Laboratories Pvt Ltd
New Products
Tubulysin M Tubulysin B Tubulysin D 2,2-diethoxyethanethioamide Potassium HMDS (1.0 M in THF) (S)-3-Aminobutanenitrile hydrochloride 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 1-(1,1-Difluoroethyl)-2-fluorobenzene 3,6-Dihydro-2H-pyran-4-carbonitrile 4-(Benzyloxy)-3-bromophenylacetic Acid Cyclobutanamine, 3,3-difluoro- (9CI) 2,3-dichloro-6- nitrobenzonitrile 1-(4-amino-2- methylbenzoyl)-7- chloro-3,4-dihydro- 1H-benzo[b] azepin-5(2H)-one 3-(4-Chloro-butyryl) -1H-indole-5- carbonitrile 7-chloro-1- (2-methyl-4- nitrobenzoyl)-3,4- dihydro-1H-benzo[b] azepin-5(2H)-one 1-Aminoindan Hydrochloride (+/-)-2, 6-Diamino-4,5,6,7 -tetrahydro Benzothiazole 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile (R)-methyl 2-isocyano-3-(tritylthio)propanoate (R)-methyl 2-formamido-3-(tritylthio)propanoate Quetiapine EP Impurity B | Quetiapine USP Related Compound B EZETIMIBE (RSS) ISOMERRelated products of tetrahydrofuran
You may like
-
694499-26-8 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 98%View Details
694499-26-8 -
3-(4-Chloro-butyryl) -1H-indole-5- carbonitrileView Details
276863-95-7 -
Ethyl 5-Aminobenzofuran-2- CarboxylateView Details
174775-48-5 -
BenzofuranView Details
271-89-6 -
(2,3-Dihydro- benzofuran-5-yl)- ethanolView Details
87776-76-9 -
3-(S)-(+)- (1-Cyano-1,1- diphenylmethyl)- 1-tosylpyrrolidineView Details
133099-09-9 -
2,3-dichloro-6- nitrobenzonitrileView Details
2112-23-2 -
2,3-Dichloro-6- nitrobenzylamine HydrochlorideView Details
70380-49-3