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HomeProduct name list3,5-Difluorophenylboronic acid

3,5-Difluorophenylboronic acid

Synonym(s):(3,5-Difluorophenyl)dihydroxyborane;3,5-Difluorobenzeneboronic acid

  • CAS NO.:156545-07-2
  • Empirical Formula: C6H5BF2O2
  • Molecular Weight: 157.91
  • MDL number: MFCD01318138
  • EINECS: 605-060-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-03 14:46:32
3,5-Difluorophenylboronic acid Structural

What is 3,5-Difluorophenylboronic acid?

Chemical properties

White to beige-yellowish powder

The Uses of 3,5-Difluorophenylboronic acid

3,5-Difluorophenylboronic Acid is used in the synthesis of N-thiazol-2-yl-benzamides as glucokinase (GK) activators for treatment of type 2 diabetes mellitus (T2DM).

The Uses of 3,5-Difluorophenylboronic acid

Intermediates of Liquid Crystals

The Uses of 3,5-Difluorophenylboronic acid

Reactant involved in:• ;Synthesis of honokiol analogs as angiogenesis inhibitors1• ;Homo-coupling reactions2• ;Suzuki-Miyaura cross-coupling reactions3• ;Enantioselective borane reduction of trifluoroacetophenone4

The Uses of 3,5-Difluorophenylboronic acid

suzuki reaction

Properties of 3,5-Difluorophenylboronic acid

Melting point: 210-217 °C (lit.)
Boiling point: 266.9±50.0 °C(Predicted)
Density  1.35±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  powder
pka 6.46±0.10(Predicted)
color  White to Orange to Green
BRN  6800882
CAS DataBase Reference 156545-07-2(CAS DataBase Reference)

Safety information for 3,5-Difluorophenylboronic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3,5-Difluorophenylboronic acid

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