3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
Synonym(s):Dencichine;3-[(Carboxycarbonyl)amino]-L-alanine;Dencichin;ODAP;Nβ-Oxalylamino-L-alanine
- CAS NO.：5302-45-4
- Empirical Formula: C5H8N2O5
- Molecular Weight: 176.13
- MDL number: MFCD00055228
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:17
What is 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID?
Description
β-ODAP stands for?L-β-N-oxalyl-α,β-diaminopropionic acid. Also called?L-β-oxalylaminoanaline, it is an analogue of the neurotransmitter glutamic acid.
β-ODAP is a neurotoxin that causes lathyrism, a disease in which neurons in the lumbar spine deteriorate, paralyzing the legs of humans and other mammals. The name lathyrism comes from the grass pea?Lathyrus sativus?and other plants of the?Lathyrus?genus that contain β-ODAP.
β-ODAP is purported to have?poisoned Christopher J. McCandless, the subject of the book and film?Into the Wild. The controversy revolves around whether β-ODAP is present in the seeds of the Alaskan wild potato?Hedysarum alpinum?that McCandless may have eaten. Thus far, analytical studies, chiefly by high-performance liquid chromatography and mass spectrometry methods, have been inconclusive. Stay tuned!
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Definition
ChEBI: An Nbeta-acyl-L-2,3-diaminopropionic acid in which the acyl group is oxalyl.
Properties of 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
| Density | 1.596±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | 0.1 M HCl: soluble2mg/mL, clear (warmed) |
| form | powder |
| pka | 1.99±0.10(Predicted) |
| color | white to beige |
| optical activity | [α]/D -17 to -23°, c = 0.5 (Solvent: 4N HCl) |
Safety information for 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
Computed Descriptors for 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
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