3-Methoxysalicylic acid

Synonym(s):3-Methoxysalicylic acid

CAS NO.：877-22-5
Empirical Formula: C8H8O4
Molecular Weight: 168.15
MDL number: MFCD00002445
EINECS: 212-888-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:01:11

What is 3-Methoxysalicylic acid?

Chemical properties

beige powder

The Uses of 3-Methoxysalicylic acid

o-Vanillic Acid, is a derivative of Vanillic Acid (V097350), used as a flavoring agent. o-Vanillic Acid, is also a building block used for the synthesis of more complex pharmaceutical compounds such as Warfarin (W498500), and Phenprocoumon (P318820).

The Uses of 3-Methoxysalicylic acid

2-Hydroxy-3-methoxybenzoic acid was used as internal standard during the simultaneous quantification of acetylsalicylic acid and its metabolite salicylic acid in human plasma by high-performance liquid chromatography. It was used in large-scale synthesis of 7-methoxy-3(2H)-benzofuranone.

Definition

ChEBI: 3-methoxysalicylic acid is benzoic acid substituted with a hydroxy group at position C-2 and a methoxy group at position C-3. It has a role as a metabolite.

Properties of 3-Methoxysalicylic acid

Melting point:	147-150 °C(lit.)
Boiling point:	217.07°C (rough estimate)
Density	1.1816 (rough estimate)
refractive index	1.4611 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	2.85±0.10(Predicted)
form	Solid
color	Off-White to Beige
BRN	2209642
CAS DataBase Reference	877-22-5(CAS DataBase Reference)

Safety information for 3-Methoxysalicylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.