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HomeProduct name list3-Fluoro-4-methoxyaniline

3-Fluoro-4-methoxyaniline

Synonym(s):3-Fluoro-4-methoxyaniline

  • CAS NO.:366-99-4
  • Empirical Formula: C7H8FNO
  • Molecular Weight: 141.14
  • MDL number: MFCD00075040
  • EINECS: 627-615-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-13 18:13:23
3-Fluoro-4-methoxyaniline Structural

What is 3-Fluoro-4-methoxyaniline?

Chemical properties

light beige to yellow-brown crystalline powder

The Uses of 3-Fluoro-4-methoxyaniline

3-Fluoro-4-methoxyaniline was used as a reagent in the synthesis of novel leucine ureido derivatives which have potent inhibitory activity againt aminopeptidase N. Also used in the synthesis of novel mGluR1 antagonists for the treatment of chronic pain.

General Description

Arrhenius parameter has been measured for the reactions of 3-fluoro-p-anisidine (3-fluoro-4-methoxyaniline) with picryl chloride.

Properties of 3-Fluoro-4-methoxyaniline

Melting point: 81-83 °C (lit.)
Boiling point: 135 °C/18 mmHg (lit.)
Density  1.1382 (estimate)
Flash point: >110°C
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Crystalline Powder
pka 4.18±0.10(Predicted)
color  Light beige to yellow-brown
BRN  2717083
CAS DataBase Reference 366-99-4(CAS DataBase Reference)

Safety information for 3-Fluoro-4-methoxyaniline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-Fluoro-4-methoxyaniline

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