3-Amino-5-hydroxypyrazole

CAS NO.：6126-22-3
Empirical Formula: C3H5N3O
Molecular Weight: 99.09
MDL number: MFCD00022384
EINECS: 228-095-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-Amino-5-hydroxypyrazole?

Chemical properties

yellow-beige to beige-brown crystalline powder

The Uses of 3-Amino-5-hydroxypyrazole

3-Amino-5-hydroxypyrazole was used in the synthesis of 2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide and heteroaromatic 3-hydroxy-5,6-diphenylpyrazolo[3,4-b]pyridines.

The Uses of 3-Amino-5-hydroxypyrazole

Amino-substituted heterocyclic compound with moderate alanine racemase inhibitory activity.

What are the applications of Application

3-Amino-5-hydroxypyrazole is used in the synthesis of 2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide and heteroaromatic 3-hydroxy-5,6-diphenylpyrazolo[3,4-b]pyridines

General Description

Molecular and vibrational structure of 3-amino-5-hydroxypyrazole was investigated by density functional method.

Properties of 3-Amino-5-hydroxypyrazole

Melting point:	214 °C (dec.) (lit.)
Boiling point:	185.55°C (rough estimate)
Density	1.3131 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka	12.37±0.40(Predicted)
form	Crystalline Powder
color	Yellow-beige to beige-brown
BRN	507793
CAS DataBase Reference	6126-22-3(CAS DataBase Reference)

Safety information for 3-Amino-5-hydroxypyrazole

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.