3-ACETYLDEOXYNIVALENOL

Synonym(s):3α-Acetoxy-7α,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one;3α-Acetylvomitoxin;3-AcDON;3-ADON

CAS NO.：50722-38-8
Empirical Formula: C17H22O7
Molecular Weight: 338.35
MDL number: MFCD28143209
EINECS: 621-771-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 09:02:00

What is 3-ACETYLDEOXYNIVALENOL?

Chemical properties

Solid

The Uses of 3-ACETYLDEOXYNIVALENOL

3-Acetyldeoxynivalenol is a trichothecene mycotoxin that is produced in a plant-pathogenic fungus, Fusarium graminearum Schwabe.

The Uses of 3-ACETYLDEOXYNIVALENOL

3-Acetyldeoxynivalenol solution may be used as an analytical reference standard for the quantification of the analyte in bovine milk using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).

Definition

ChEBI: 3-acetyldeoxynivalenol is a trichothecene mycotoxin that is deoxynivalenol acetylated on the oxygen at C-3. A skin and eye irritant, along with its 15-acetyl regioisomer and its parent deoxynivalenol it is considered among the most commonly and widely distributed cereal contaminants. It has a role as an epitope and a mycotoxin. It is functionally related to a deoxynivalenol.

General Description

3-Acetyldeoxynivalenol is a trichothecene mycotoxin, secreted by Fusarium species. It stimulates the activation of c-Jun N-terminal kinase (JNK)/ p38 mitogen-activated protein kinases and prevents protein synthesis. 3-Acetyldeoxynivalenol is a weak inducer of apoptosis.

Properties of 3-ACETYLDEOXYNIVALENOL

Melting point:	185.75°C
Boiling point:	394.5°C (rough estimate)
Density	1.2179 (rough estimate)
refractive index	1.4790 (estimate)
Flash point:	2 °C
storage temp.	-20°C
solubility	DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
pka	11.84±0.70(Predicted)
form	neat

Safety information for 3-ACETYLDEOXYNIVALENOL

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H300:Acute toxicity,oral
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.