2,4,6-Trimethylbenzoic acid

Synonym(s):2-Mesitylenecarboxylic acid

CAS NO.：480-63-7
Empirical Formula: C10H12O2
Molecular Weight: 164.2
MDL number: MFCD00002481
EINECS: 207-553-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 2,4,6-Trimethylbenzoic acid?

Chemical properties

white to almost white crystalline powder

The Uses of 2,4,6-Trimethylbenzoic acid

Mesitoic acid can be used for its antioxidant.

Definition

ChEBI: A trimethylbenzoic acid in which the three methyl substituents are located at positions 2, 4 and 6.

Synthesis Reference(s)

Journal of the American Chemical Society, 96, p. 590, 1974 DOI: 10.1021/ja00809a049
Organic Syntheses, Coll. Vol. 3, p. 553, 1955
Tetrahedron Letters, 11, p. 4459, 1970

Purification Methods

Crystallise mesitoic acid from water, ligroin or carbon tetrachloride [Ohwada et al. J Am Chem Soc 108 3029 1986]. [Beilstein 9 H 553, 9 I 214, 9 II 360, 9 III 2489, 9 IV 1854.]

Properties of 2,4,6-Trimethylbenzoic acid

Melting point:	152-155 °C (lit.)
Boiling point:	288.61°C (estimate)
Density	1.0670 (estimate)
refractive index	1.5198 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chlorform (Slightly), Methanol (Slightly)
form	Solid
pka	pK1:3.448 (25°C)
color	White to Off-White
Water Solubility	722.5mg/L(temperature not stated)
BRN	1866187
CAS DataBase Reference	480-63-7(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2,4,6-trimethyl-(480-63-7)
EPA Substance Registry System	2,4,6-Trimethylbenzoic acid (480-63-7)

Safety information for 2,4,6-Trimethylbenzoic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.