Benzoic acid
Synonym(s):Acidum benzoicum;Benzoic acid;Benzoic acid solution;Phenylformic acid, Benzene carboxylic acid
- CAS NO.:65-85-0
- Empirical Formula: C7H6O2
- Molecular Weight: 122.12
- MDL number: MFCD00002398
- EINECS: 200-618-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-09 14:42:29
What is Benzoic acid?
Description
Benzoic acid, the simplest benzene-based carboxylic acid, has been known since the 16th century. One of its discoverers was the legendary clairvoyant Nostradamus. Its most common natural source is gum benzoin, a resin found in the bark of trees of the genus Styrax.
The Uses of Benzoic acid
Benzoic acid is a simple organic compound employed as a preservative. Benzoic acid and sodium benzoate (C6H5COONa) are used as food preservatives and added to foods, juices, and beverages that are acidic. It also is often found in topical antifungal preparations.
Background
As a fungistatic compound Benzoic acid is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo.
Production
Sodium benzoate is an important benzoic acid derivative produced industrially by neutralization of benzoic acid using sodium hydroxide or sodium bicarbonate solution. Calcium benzoate, potassium benzoate, and other benzoate salts are also produced. Its first industrial synthesis was the hydrolysis of benzotrichloride to calcium benzoate, followed by acidification. This method has been completely displaced by the air oxidation of toluene, which avoids the problem of product contamination with chlorinated byproducts.
Properties of Benzoic acid
Melting point: | 121-125 °C(lit.) |
Boiling point: | 249 °C(lit.) |
Density | 1.08 |
Flash point: | 250 °F |
storage temp. | 2-8°C |
solubility | soluble, clear, colorless (95% ethanol, 1gm/3mL) |
form | Solid |
appearance | white crystals |
color | White to yellow-beige to orange |
Water Solubility | Slightly soluble. 0.34 g/100 mL |
Safety information for Benzoic acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Health Hazard GHS08 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H372:Specific target organ toxicity, repeated exposure |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Benzoic acid
InChIKey | WPYMKLBDIGXBTP-UHFFFAOYSA-N |
Abamectin manufacturer
Nagar Haveli Perfumes & Aromatics
ADVENT CHEMBIO PRIVATE LIMITED
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