2,4,6-Trichlorobenzoic acid

CAS NO.：50-43-1
Empirical Formula: C7H3Cl3O2
Molecular Weight: 225.46
MDL number: MFCD00060699
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-11 17:04:31

What is 2,4,6-Trichlorobenzoic acid?

Chemical properties

beige to light brown crystalline powder

The Uses of 2,4,6-Trichlorobenzoic acid

2,4,6-Trichlorobenzoic acid can be used as reactant involved in Active-sodium-promoted reductive cleavage of halogenated benzoic acids; Synthesis of aryl aminopyrazole benzamides for use as non-steroidal selective glucocorticoid receptor agonists ; Flame retardant monomer synthesis; Synthesis of 3,4,7-trisubstituted coumarins for use as antifungals and Solid-phase synthesis of saphenamycin analogs with antimicrobial activity.

The Uses of 2,4,6-Trichlorobenzoic acid

2,4,6-Trichlorobenzoic Acid is a possible degradation intermediate of Polychlorinated Biphenyls (PCBs) in contaminated soil, suggesting the occurrence of microbial transformation processes over time.

The Uses of 2,4,6-Trichlorobenzoic acid

Reactant involved in:

Active-sodium-promoted reductive cleavage of halogenated benzoic acids
Synthesis of aryl aminopyrazole benzamides for use as non-steroidal selective glucocorticoid receptor agonists
Flame retardant monomer synthesis
Synthesis of 3,4,7-trisubstituted coumarins for use as antifungals
Solid-phase synthesis of saphenamycin analogs with antimicrobial activity

Cocatalyst for cis-dihydroxylation and epoxidation of alkenes

General Description

Structure and hydrogen bonding pattern in 2,4,6-trichlorobenzoic acid is reported.

Properties of 2,4,6-Trichlorobenzoic acid

Melting point:	160-164 °C (lit.)
Boiling point:	329.7±37.0 °C(Predicted)
Density	1.5599 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	1.40±0.25(Predicted)
color	White to Light yellow to Light orange
BRN	1874127
CAS DataBase Reference	50-43-1(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2,4,6-trichloro-(50-43-1)
EPA Substance Registry System	2,4,6-Trichlorobenzoic acid (50-43-1)

Safety information for 2,4,6-Trichlorobenzoic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.