2,4-Dichloro-6,7-dimethoxyquinazoline
Synonym(s):2,4-Dichloro-6,7-dimethoxyquinazoline
- CAS NO.：27631-29-4
- Empirical Formula: C10H8Cl2N2O2
- Molecular Weight: 259.09
- MDL number: MFCD00051733
- EINECS: 608-117-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2,4-Dichloro-6,7-dimethoxyquinazoline?
Chemical properties
pale yellow to beige crystalline powder
The Uses of 2,4-Dichloro-6,7-dimethoxyquinazoline
2,4-Dichloro-6,7-dimethoxyquinazoline is used as an intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. It is also used as an intermediate in the preparation of terazosin.
The Uses of 2,4-Dichloro-6,7-dimethoxyquinazoline
An intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. An intermediate in the preparation of Terazosin (T105000).
Properties of 2,4-Dichloro-6,7-dimethoxyquinazoline
| Melting point: | 175-178 °C (lit.) |
| Boiling point: | 340.5±42.0 °C(Predicted) |
| Density | 1.5369 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | -0.49±0.30(Predicted) |
| color | Pale yellow to beige |
| Water Solubility | Insoluble in water. |
| Sensitive | Moisture Sensitive |
| BRN | 190331 |
| CAS DataBase Reference | 27631-29-4(CAS DataBase Reference) |
Safety information for 2,4-Dichloro-6,7-dimethoxyquinazoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,4-Dichloro-6,7-dimethoxyquinazoline
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