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HomeProduct name list2-Thiophenesulfonyl chloride

2-Thiophenesulfonyl chloride

  • CAS NO.:16629-19-9
  • Empirical Formula: C4H3ClO2S2
  • Molecular Weight: 182.65
  • MDL number: MFCD00005426
  • EINECS: 240-677-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:38
2-Thiophenesulfonyl chloride Structural

What is 2-Thiophenesulfonyl chloride?

Chemical properties

2-Thiophenesulfonyl chloride is colorless to brown low melting solid or liquid

The Uses of 2-Thiophenesulfonyl chloride

2-Thiophenesulfonyl chloride has been used in the preparation of 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene

The Uses of 2-Thiophenesulfonyl chloride

2-Thiophenesulfonyl chloride is a compound used in the preparation of various pharmaceuticals. Thiophene-2-sulfonyl Chloride was used as an intermediate in the synthesis of β-Cell apoptosis supressor .

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 3286, 1974 DOI: 10.1021/jo00936a030

General Description

Kinetics of reactions of 2-thiophenesulfonyl chloride with substituted anilines in methanol has been reported. Kinetics of solvolysis of 2-thiophenesulfonyl chloride in binary solvent mixtures has been studied.

Properties of 2-Thiophenesulfonyl chloride

Melting point: 30-32 °C(lit.)
Boiling point: 130-132 °C14 mm Hg(lit.)
Density  1.534 (estimate)
refractive index  1.5722-1.5742
Flash point: >110°C
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  soluble in Chloroform, Ethyl Acetate
form  solid
color  White to Almost white
Water Solubility  Reacts with water.
Sensitive  Moisture Sensitive
BRN  123536
Stability: Moisture sensitive
CAS DataBase Reference 16629-19-9(CAS DataBase Reference)
NIST Chemistry Reference 2-Thiophene sulfonyl chloride(16629-19-9)
EPA Substance Registry System 2-Thiophenesulfonyl chloride (16629-19-9)

Safety information for 2-Thiophenesulfonyl chloride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Thiophenesulfonyl chloride

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