2-Methyleneglutaronitrile

CAS NO.：1572-52-7
Empirical Formula: C6H6N2
Molecular Weight: 106.13
MDL number: MFCD00001869
EINECS: 216-391-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-08 14:03:24

What is 2-Methyleneglutaronitrile?

Description

2-Methyleneglutaronitrile [1572-52-7], acrylonitrile dimer, 2,4-dicyano-1-butene, 2- methylenepentanedinitrile, NCC2H4C (=CH2) CN, is a colorless liquid slightly miscible with water, ethanol, acetone and benzene, immiscible with hexane.

Chemical properties

Colorless liquid.Slightly soluble in water; insoluble in aliphatic andalicyclic hydrocarbons, soluble in aromatic hydro-carbons and polar organic solvents.

The Uses of 2-Methyleneglutaronitrile

Vinyl monomer for polymerization and copoly-merization, intermediate in making fibers and phar-maceuticals.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 4591, 1987 DOI: 10.1016/S0040-4039(00)96573-0

Synthesis

2-Methyleneglutaronitrile is obtained by dimerization of acrylonitrile in the presence of a metal halide and a tertiary amine. Its hydrogenation yields 2-methylglutaronitrile, which in turn can be converted into 3-methylpyridine.

Properties of 2-Methyleneglutaronitrile

Melting point:	−9.6 °C(lit.)
Boiling point:	254 °C(lit.)
Density	0.976 g/mL at 25 °C(lit.)
refractive index	n20/D 1.456(lit.)
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
CAS DataBase Reference	1572-52-7(CAS DataBase Reference)
NIST Chemistry Reference	Pentanedinitrile, 2-methylene-(1572-52-7)
EPA Substance Registry System	Pentanedinitrile, 2-methylene- (1572-52-7)

Safety information for 2-Methyleneglutaronitrile

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…