2-Ketoglutaric acid
Synonym(s):2-Ketoglutaric acid;2-Oxoglutaric acid;2-Oxopentanedioic acid;alpha-Ketoglutarate;alpha-Ketoglutaric acid
- CAS NO.:328-50-7
- Empirical Formula: C5H6O5
- Molecular Weight: 146.1
- MDL number: MFCD00004165
- EINECS: 206-330-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-25 09:45:49
What is 2-Ketoglutaric acid?
Description
2-Ketoglutaric acid also known as α-Ketoglutaric acid (AKG) is a chemical found in the body. It is a ketone derivative of the organic compound glutaric acid. It is important for the proper metabolism of all essential amino acids and the transfer of cellular energy in the citric acid or Krebs cycle. In combination with L-glutamate, AKG can reduce levels of ammonia formed in the brain, muscles, and kidneys, as well as help balance the body’s nitrogen chemistry and prevent nitrogen excess in body tissues and fluids.
α-Ketoglutaric acid is used for kidney disease; intestinal and stomach disorders, including bacterial infections; liver problems; cataracts; and recurring yeast infections. It is also used for improving the way kidney patients receiving hemodialysis treatments process protein.
The Uses of 2-Ketoglutaric acid
2-Ketoglutaric acid has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries. It is used as an intermediate in the kreb's cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis.
What are the applications of Application
α-Ketoglutaric Acid is a derivative of glutaric acid
Properties of 2-Ketoglutaric acid
Melting point: | 113-115 °C |
Boiling point: | 185.67°C (rough estimate) |
Density | 1.2821 (rough estimate) |
storage temp. | 2-8°C |
solubility | H2O: soluble0.1g/mL, clear, colorless |
form | Crystalline Powder |
color | White to slightly yellow |
Odor | Odorless |
Water Solubility | Soluble in water, methanol and dimethyl sulfoxide. |
Safety information for 2-Ketoglutaric acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2-Ketoglutaric acid
InChIKey | KPGXRSRHYNQIFN-UHFFFAOYSA-N |
Abamectin manufacturer
JIVICHEM SYNTHESIS PVT LTD
JSK Chemicals
S D Fine Chem Limited
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 3-NITRO-5-ACETYL IMINODIBENZYL 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE) 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THFRelated products of tetrahydrofuran
You may like
-
328-50-7 ALPHA-Ketoglutaric acid 98%View Details
328-50-7 -
328-50-7 98%View Details
328-50-7 -
alpha-Ketoglutaric acid, 98% 99%View Details
328-50-7 -
ALPHA-Ketoglutaric acid 99%View Details
328-50-7 -
Desloratadine 99%View Details
100643-71-8 -
175481-36-4 Lacosamide 99%View Details
175481-36-4 -
135046-48-9 99%View Details
135046-48-9 -
Rupatadine Fumarate 99%View Details
182349-12-8