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HomeProduct name list2-Hydroxy-4-methylpyridine

2-Hydroxy-4-methylpyridine

Synonym(s):4-Methyl-2(1H)-pyridinone

  • CAS NO.:13466-41-6
  • Empirical Formula: C6H7NO
  • Molecular Weight: 109.13
  • MDL number: MFCD00134298
  • EINECS: 627-289-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-09 13:47:46
2-Hydroxy-4-methylpyridine Structural

What is 2-Hydroxy-4-methylpyridine?

Chemical properties

off-white to light brown crystalline powder

The Uses of 2-Hydroxy-4-methylpyridine

2-Hydroxy-4-methylpyridine is an intermediate used to prepare oxobenzopyrancarboxylate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino)(pyridinyloxy)pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists.

Definition

ChEBI: 2-Hydroxy-4-methylpyridine is a member of methylpyridines.

Properties of 2-Hydroxy-4-methylpyridine

Melting point: 131-134 °C (lit.)
Boiling point: 186-187 °C/12 mmHg (lit.)
Density  1.1143 (rough estimate)
refractive index  1.5444 (estimate)
Flash point: 186-187°C/12mm
storage temp.  Inert atmosphere,Room Temperature
pka pK1:4.529(+1) (25°C)
form  powder to crystal
color  White to Gray to Brown
BRN  107082
CAS DataBase Reference 13466-41-6(CAS DataBase Reference)

Safety information for 2-Hydroxy-4-methylpyridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Hydroxy-4-methylpyridine

InChIKey YBDRFJXGJQULGH-UHFFFAOYSA-N

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