2-Hydroxy-4-methylpyridine
Synonym(s):4-Methyl-2(1H)-pyridinone
- CAS NO.：13466-41-6
- Empirical Formula: C6H7NO
- Molecular Weight: 109.13
- MDL number: MFCD00134298
- EINECS: 627-289-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-09 13:47:46
What is 2-Hydroxy-4-methylpyridine?
Chemical properties
off-white to light brown crystalline powder
The Uses of 2-Hydroxy-4-methylpyridine
2-Hydroxy-4-methylpyridine is an intermediate used to prepare oxobenzopyrancarboxylate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino)(pyridinyloxy)pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists.
Definition
ChEBI: 2-Hydroxy-4-methylpyridine is a member of methylpyridines.
Properties of 2-Hydroxy-4-methylpyridine
| Melting point: | 131-134 °C (lit.) |
| Boiling point: | 186-187 °C/12 mmHg (lit.) |
| Density | 1.1143 (rough estimate) |
| refractive index | 1.5444 (estimate) |
| Flash point: | 186-187°C/12mm |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | pK1:4.529(＋1) (25°C) |
| form | powder to crystal |
| color | White to Gray to Brown |
| BRN | 107082 |
| CAS DataBase Reference | 13466-41-6(CAS DataBase Reference) |
Safety information for 2-Hydroxy-4-methylpyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Hydroxy-4-methylpyridine
| InChIKey | YBDRFJXGJQULGH-UHFFFAOYSA-N |
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