2-Hydroxy-6-methylpyridine

Synonym(s):6-Methyl-2-pyridinol;6-Methyl-2-pyridone

CAS NO.：3279-76-3
Empirical Formula: C6H7NO
Molecular Weight: 109.13
MDL number: MFCD00456278
EINECS: 221-919-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-14 14:43:47

What is 2-Hydroxy-6-methylpyridine?

Chemical properties

white to cream-colored crystalline powder

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 1186, 1949 DOI: 10.1021/ja01172a014

General Description

2-Hydroxy-6-methylpyridine reacts with carboxylic acids RCOOH to give an equilibrium mixture of products M(2)(O(2)CR)(n)(mhp)(4-n) where R = 2-thienyl and phenyl. mhp is the anion formed from deprotonation of 2-hydroxy-6-methylpyridine.

Properties of 2-Hydroxy-6-methylpyridine

Melting point:	157-159 °C (lit.)
Boiling point:	131-133C
Density	1.1143 (rough estimate)
refractive index	1.5040 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	Crystalline Powder
pka	12.12±0.10(Predicted)
color	White to cream
BRN	107073
InChI	InChI=1S/C6H7NO/c1-5-3-2-4-6(8)7-5/h2-4H,1H3,(H,7,8)
CAS DataBase Reference	3279-76-3(CAS DataBase Reference)
NIST Chemistry Reference	2(1H)-Pyridinone, 6-methyl-(3279-76-3)

Safety information for 2-Hydroxy-6-methylpyridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.