2-Hydroxy-6-methylpyridine
Synonym(s):6-Methyl-2-pyridinol;6-Methyl-2-pyridone
- CAS NO.：3279-76-3
- Empirical Formula: C6H7NO
- Molecular Weight: 109.13
- MDL number: MFCD00456278
- EINECS: 221-919-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 2-Hydroxy-6-methylpyridine?
Chemical properties
white to cream-colored crystalline powder
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 1186, 1949 DOI: 10.1021/ja01172a014
General Description
2-Hydroxy-6-methylpyridine reacts with carboxylic acids RCOOH to give an equilibrium mixture of products M(2)(O(2)CR)(n)(mhp)(4-n) where R = 2-thienyl and phenyl. mhp is the anion formed from deprotonation of 2-hydroxy-6-methylpyridine.
Properties of 2-Hydroxy-6-methylpyridine
| Melting point: | 157-159 °C (lit.) |
| Boiling point: | 131-133C |
| Density | 1.1143 (rough estimate) |
| refractive index | 1.5040 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| pka | 12.12±0.10(Predicted) |
| color | White to cream |
| BRN | 107073 |
| InChI | InChI=1S/C6H7NO/c1-5-3-2-4-6(8)7-5/h2-4H,1H3,(H,7,8) |
| CAS DataBase Reference | 3279-76-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2(1H)-Pyridinone, 6-methyl-(3279-76-3) |
Safety information for 2-Hydroxy-6-methylpyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Hydroxy-6-methylpyridine
| InChIKey | JEAVIRYCMBDJIU-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(C)=CC=C1 |
2-Hydroxy-6-methylpyridine manufacturer
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ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
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ASM Organics
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product: 2-Hydroxy-6-Methylpyridine
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