2-Fluoro-3-(trifluoromethyl)aniline

Synonym(s):α,α,α,2-Tetrafluoro-m-toluidine;3-Amino-2-fluorobenzotrifluoride

CAS NO.：123973-25-1
Empirical Formula: C7H5F4N
Molecular Weight: 179.11
MDL number: MFCD00061241
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

2-Fluoro-3-(trifluoromethyl)aniline Structural

What is 2-Fluoro-3-(trifluoromethyl)aniline?

Chemical properties

clear yellow liquid

The Uses of 2-Fluoro-3-(trifluoromethyl)aniline

2-Fluoro-3-(trifluoromethyl)aniline is a buliding block for various inhibitors such as 5,6,7-Trimethoxy-N-phenyl(ethyl)-4-aminoquinazoline derivatives that have anticancer activities and N-[3-(Phenylcarbamoyl)aryl]pyrimidine-5-carboxamide that are lymphocyte-specific kinase inhibitors.

The Uses of 2-Fluoro-3-(trifluoromethyl)aniline

2-Fluoro-3-(trifluoromethyl)aniline may be used in chemical synthesis.

Properties of 2-Fluoro-3-(trifluoromethyl)aniline

Boiling point:	189 °C (lit.)
Density	1.39 g/mL at 25 °C (lit.)
refractive index	n20/D 1.462(lit.)
Flash point:	180 °F
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Oil
pka	1.98±0.10(Predicted)
Specific Gravity	1.390
color	Colourless
CAS DataBase Reference	123973-25-1(CAS DataBase Reference)

Safety information for 2-Fluoro-3-(trifluoromethyl)aniline

Signal word	Warning
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H302:Acute toxicity,oral H311:Acute toxicity,dermal H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P309:IF exposed or if you feel unwell: P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.