4-Fluorobenzotrifluoride
Synonym(s):α,α,α,4-Tetrafluorotoluene
- CAS NO.：402-44-8
- Empirical Formula: C7H4F4
- Molecular Weight: 164.1
- MDL number: MFCD00000399
- EINECS: 206-944-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is 4-Fluorobenzotrifluoride?
Chemical properties
Clear colourless to light yellow liquid
The Uses of 4-Fluorobenzotrifluoride
4-Fluorobenzotrifluoride was used in the synthesis of 2,2?-bis(trifluoromethylphenoxy)biphenyl via nucleophilic aromatic substitution reaction with 2,2?-biphenol, (S)-fluoxetine, potent inhibitor of neuronal serotonin-uptake and 1-aryloxy-2-substituted aminomethyltetrahydronaphthalene derivatives.
Synthesis Reference(s)
Tetrahedron, 49, p. 8129, 1993 DOI: 10.1016/S0040-4020(01)88032-7
Properties of 4-Fluorobenzotrifluoride
| Melting point: | −42-−41.7 °C(lit.) |
| Boiling point: | 102-105 °C(lit.) |
| Density | 1.293 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 51 °F |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1.2930 |
| Water Solubility | Slightly soluble in water. |
| BRN | 1909390 |
| CAS DataBase Reference | 402-44-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-fluoro-4-(trifluoromethyl)-(402-44-8) |
| EPA Substance Registry System | 4-Fluorobenzotrifluoride (402-44-8) |
Safety information for 4-Fluorobenzotrifluoride
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Fluorobenzotrifluoride
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
4-Fluorobenzotrifluoride CAS 402-44-8View Details
402-44-8 -
4-Fluorobenzotrifluoride CAS 402-44-8View Details
402-44-8 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.