2'-Fluoro-2'-deoxyuridine
- CAS NO.:784-71-4
- Empirical Formula: C9H11FN2O5
- Molecular Weight: 246.19
- MDL number: MFCD01317293
- EINECS: 1806241-263-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 11:41:24
What is 2'-Fluoro-2'-deoxyuridine?
Description
2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity.
Chemical properties
White to almost white crystalline powder
The Uses of 2'-Fluoro-2'-deoxyuridine
2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.
The Uses of 2'-Fluoro-2'-deoxyuridine
A component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.
Properties of 2'-Fluoro-2'-deoxyuridine
Melting point: | 147.0 to 153.0 °C |
Density | 1.63±0.1 g/cm3(Predicted) |
refractive index | 53 ° (C=0.3, H2O) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Soluble in methanol. |
pka | 9.39±0.10(Predicted) |
form | Powder |
color | White to Off-white |
InChI | InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1 |
CAS DataBase Reference | 784-71-4(CAS DataBase Reference) |
Safety information for 2'-Fluoro-2'-deoxyuridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for 2'-Fluoro-2'-deoxyuridine
InChIKey | UIYWFOZZIZEEKJ-XVFCMESISA-N |
SMILES | OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](F)[C@@H]1O |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
2'-Deoxyuridine
BrdU (Bromodeoxyuridine)
uridine diphosphate glucose {= UDP-glucose}
5-Fluoro-2'-deoxyuridine 98%,(+)-5-FLUORO-2'-DEOXYURIDINE,5-FLUORO-2'-DEOXYURIDINE,5-FLUORO-2-DEOXYURIDINE,beta-5-fluoro-2’-deoxyuridin
fluoro jade
Fluorine
Trifluridine
Doxifluridine
You may like
-
2'-Fluoro-2'-deoxyuridine CAS 784-71-4View Details
784-71-4 -
2'-Deoxy-2'-fluorouridine CAS 784-71-4View Details
784-71-4 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.