2-Dimethylaminoethyl chloride hydrochloride

Synonym(s):N-(2-Chloroethyl)dimethylamine hydrochloride;1-Chloro-2-dimethylaminoethane hydrochloride;2-(Dimethylamino)ethyl chloride hydrochloride;Dimethylaminoethyl chloride hydrochloride, N,N-Dimethyl-N-2-chloroethylammonium chloride;N-(2-Chloroethyl)-N,N-dimethylammonium chloride

CAS NO.：4584-46-7
Empirical Formula: C4H11Cl2N
Molecular Weight: 144.04
MDL number: MFCD00012516
EINECS: 224-970-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:32

2-Dimethylaminoethyl chloride hydrochloride Structural

What is 2-Dimethylaminoethyl chloride hydrochloride?

Chemical properties

Colorless to beige crystals

The Uses of 2-Dimethylaminoethyl chloride hydrochloride

2-Chloro-N,N-dimethylethylamine hydrochloride (DMC) is used as intermediate for the synthesis of pharmaceuticals (e.g. bephenium hydroxnaphthoate, diltiazem, mepyramine and phenyltoloxamine). Product Data Sheet

The Uses of 2-Dimethylaminoethyl chloride hydrochloride

2-Chloro-N,N-dimethylethylamine is a widely used as a intermediate and starting reagent for organic synthesis. Also acts as Intermediate for the syntheses of bephenium hydroxynaphthoate, diltiazem, mepyramine and phenyltoloxamine.

Definition

ChEBI: 2-dimethylaminoethyl chloride hydrochloride is a hydrochloride obtained by combining 2-dimethylaminoethyl chloride with one molar equivalent of hydrochloric acid. It is a hydrochloride and an organoammonium salt. It contains a 2-dimethylammonioethyl chloride.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx

Properties of 2-Dimethylaminoethyl chloride hydrochloride

Melting point:	201-204 °C(lit.)
storage temp.	Store below +30°C.
solubility	2000g/l
form	Crystalline Powder or Crystals
color	White to brown-yellow
Water Solubility	2000 g/L (20 ºC)
Sensitive	Hygroscopic
BRN	3591234
Stability:	Hygroscopic
CAS DataBase Reference	4584-46-7(CAS DataBase Reference)
EPA Substance Registry System	Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride (4584-46-7)

Safety information for 2-Dimethylaminoethyl chloride hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H341:Germ cell mutagenicity H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention.