2-Chloro-4-methylaniline
Synonym(s):2-Chloro-p-toluidine;4-Amino-3-chlorotoluene
- CAS NO.:615-65-6
- Empirical Formula: C7H8ClN
- Molecular Weight: 141.6
- MDL number: MFCD00007666
- EINECS: 210-440-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-25 18:09:02
What is 2-Chloro-4-methylaniline?
Chemical properties
clear yellow to pale brown liquid
Chemical properties
The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
The Uses of 2-Chloro-4-methylaniline
2-Chloro-4-methylaniline is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.
The Uses of 2-Chloro-4-methylaniline
2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry.
Safety Profile
Poison by ingestion. A severe eye and skin irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx. See also other chloro toluidine entries.
Potential Exposure
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.
Shipping
UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials
Incompatibilities
Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.
Properties of 2-Chloro-4-methylaniline
Melting point: | 7 °C (lit.) |
Boiling point: | 223-225 °C (lit.) |
Density | 1.151 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 211 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | methanol: soluble |
form | Liquid |
pka | 3.09±0.10(Predicted) |
color | Clear yellow to pale brown |
BRN | 774514 |
Stability: | Acid Sensitive, Light Sensitive |
CAS DataBase Reference | 615-65-6(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 2-chloro-4-methyl-(615-65-6) |
EPA Substance Registry System | Benzenamine, 2-chloro-4-methyl- (615-65-6) |
Safety information for 2-Chloro-4-methylaniline
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H370:Specific target organ toxicity, single exposure H372:Specific target organ toxicity, repeated exposure H373:Specific target organ toxicity, repeated exposure H402:Hazardous to the aquatic environment, acute hazard H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P307+P311:IF exposed: call a POISON CENTER or doctor/physician. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-Chloro-4-methylaniline
2-Chloro-4-methylaniline manufacturer
Aarti Industries Limited (AIL)
ALS INDIA LIFE SCIENCES
BASR Fine Chemicals Pvt. Ltd.
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