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HomeProduct name list2-Bromo-4-(trifluoromethyl)pyridine

2-Bromo-4-(trifluoromethyl)pyridine

  • CAS NO.:175205-81-9
  • Empirical Formula: C6H3BrF3N
  • Molecular Weight: 225.99
  • MDL number: MFCD00153085
  • EINECS: 672-057-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
2-Bromo-4-(trifluoromethyl)pyridine Structural

What is 2-Bromo-4-(trifluoromethyl)pyridine?

The Uses of 2-Bromo-4-(trifluoromethyl)pyridine

2-Bromo-4-(trifluoromethyl)pyridine in used in the preparation of pyrazolopyridines as kinase LRRK2 inhibitors for treating and preventing cancer and neurodegenerative diseases.

The Uses of 2-Bromo-4-(trifluoromethyl)pyridine

Regioselective deprotonation at C-3 with LDA followed by trapping with carbon dioxide provides the correspondin nicotinic acid.

Properties of 2-Bromo-4-(trifluoromethyl)pyridine

Melting point: -21--20 °C
Boiling point: 84-85 °C/14 mmHg
Density  1.827 g/mL at 25 °C
refractive index  n20/D 1.478
Flash point: 164 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  clear liquid
pka -1.57±0.10(Predicted)
color  Colorless to Light yellow to Light orange
CAS DataBase Reference 175205-81-9(CAS DataBase Reference)

Safety information for 2-Bromo-4-(trifluoromethyl)pyridine

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Bromo-4-(trifluoromethyl)pyridine

InChIKey WZVHLUMAQLUNTJ-UHFFFAOYSA-N

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