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HomeProduct name list2-Bromo-2-methylpropionic acid

2-Bromo-2-methylpropionic acid

Synonym(s):α-Bromoisobutyric acid;2-Bromo-2-methylpropionic acid

  • CAS NO.:2052-01-9
  • Empirical Formula: C4H7BrO2
  • Molecular Weight: 167
  • MDL number: MFCD00004168
  • EINECS: 218-139-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 13:37:16
2-Bromo-2-methylpropionic acid Structural

What is 2-Bromo-2-methylpropionic acid?

Chemical properties

white powder

The Uses of 2-Bromo-2-methylpropionic acid

2-Bromo-2-methylpropionic acid is used in the Herceptin functionalization of polyhedral oligomeric silsesquioxane-conjugated oligomers-silica /iron oxide nanoparticles for tumor cell sorting.

The Uses of 2-Bromo-2-methylpropionic acid

2-Bromoisobutyric acid is used in the synthesis of dextran macroinitiator for atom transfer radical polymerization (ATRP) by partial esterification of hydroxyl group of the polysaccharide. The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

General Description

The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

Properties of 2-Bromo-2-methylpropionic acid

Melting point: 44-47 °C(lit.)
Boiling point: 198-200 °C(lit.)
Density  1.43 g/cm3
refractive index  1.4570 (estimate)
Flash point: >230 °F
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  soluble in Chloroform, Methanol
pka 2.91±0.10(Predicted)
form  Liquid
color  Clear colorless to slightly yellow
Water Solubility  Soluble in alcohol and ether. Slightly soluble in water.
Merck  14,1421
BRN  1745543
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference 2052-01-9(CAS DataBase Reference)
NIST Chemistry Reference «alpha»-Bromoisobutyric acid(2052-01-9)
EPA Substance Registry System Propanoic acid, 2-bromo-2-methyl- (2052-01-9)

Safety information for 2-Bromo-2-methylpropionic acid

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Bromo-2-methylpropionic acid

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