2-Bromo-2-methylpropane

Chemical properties

CLEAR COLOURLESS TO YELLOW-BROWN LIQUID

The Uses of 2-Bromo-2-methylpropane

2-Bromo-2-methylpropane was used to study the massive deadenylation of adenine based-nucleosides induced by halogenated alkanes under physiological conditions.

The Uses of 2-Bromo-2-methylpropane

tert-Butyl bromide is used as a raw material in synthetic organic chemistry. It is used to study the massive deadenylation of adenine based-nucleosides.

General Description

A colorless liquid. Slightly denser than water and insoluble in water. Flash point between 64 - 73°F. Harmful if inhaled.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as BROMOMETHYLPROPANE, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Burning generates toxic fumes of bromine.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of BrSee also BROMIDES.

Purification Methods

Neutralise the bromomethylpropane with K2CO3, distil, and dry it using molecular sieves (5A), then distil it in a vacuum and degas it by the freeze-pump-thaw technique. Seal it under vacuum. [Beilstein 1 IV 295.]