2-Amino-3-benzyloxypyridine
- CAS NO.：24016-03-3
- Empirical Formula: C12H12N2O
- Molecular Weight: 200.24
- MDL number: MFCD00006316
- EINECS: 245-983-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is 2-Amino-3-benzyloxypyridine?
Chemical properties
Brown crystalline powder
The Uses of 2-Amino-3-benzyloxypyridine
2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors.
The Uses of 2-Amino-3-benzyloxypyridine
2-Amino-3-benzyloxypyridine was used in the synthesis of 1-acetyl-2-[2-(3-benzyloxypyridinyl)]iminoimidazolidine.
General Description
2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one.
Biochem/physiol Actions
2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity.
Properties of 2-Amino-3-benzyloxypyridine
| Melting point: | 92-94 °C (lit.) |
| Boiling point: | 337.96°C (rough estimate) |
| Density | 1.1131 (rough estimate) |
| refractive index | 1.6660 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 8.40±0.10(Predicted) |
| color | Green to brown |
| BRN | 392674 |
| CAS DataBase Reference | 24016-03-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinamine, 3-(phenylmethoxy)-(24016-03-3) |
Safety information for 2-Amino-3-benzyloxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-3-benzyloxypyridine
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