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HomeProduct name list2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine

  • CAS NO.:24016-03-3
  • Empirical Formula: C12H12N2O
  • Molecular Weight: 200.24
  • MDL number: MFCD00006316
  • EINECS: 245-983-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-01 18:09:03
2-Amino-3-benzyloxypyridine Structural

What is 2-Amino-3-benzyloxypyridine?

Chemical properties

Brown crystalline powder

The Uses of 2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine is used in preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors.

The Uses of 2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine was used in the synthesis of 1-acetyl-2-[2-(3-benzyloxypyridinyl)]iminoimidazolidine.

General Description

2-Amino-3-benzyloxypyridine on condensation with diethyl ethoxymethylene malonate affords 9-benzyloxy-3-ethoxycarbonylpyrido[1,2-a]pyrimidin-4-one.

Biochem/physiol Actions

2-Amino-3-benzyloxypyridine is an inhibitor of mitogen-activated protein kinase p38α activity.

Properties of 2-Amino-3-benzyloxypyridine

Melting point: 92-94 °C (lit.)
Boiling point: 337.96°C (rough estimate)
Density  1.1131 (rough estimate)
refractive index  1.6660 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Crystalline Powder
pka 8.40±0.10(Predicted)
color  Green to brown
BRN  392674
CAS DataBase Reference 24016-03-3(CAS DataBase Reference)
NIST Chemistry Reference 2-Pyridinamine, 3-(phenylmethoxy)-(24016-03-3)

Safety information for 2-Amino-3-benzyloxypyridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Amino-3-benzyloxypyridine

2-Amino-3-benzyloxypyridine manufacturer

JSK Chemicals

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