(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
Synonym(s):(1,3-Dioxolan-2-yl)-methyltriphenylphosphonium bromide;Triphenyl-1,3-dioxolan-2-ylmethylphosphonium bromide
- CAS NO.:52509-14-5
- Empirical Formula: C22H22BrO2P
- Molecular Weight: 429.29
- MDL number: MFCD00011966
- EINECS: 257-977-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-17 21:30:02
What is (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide?
Chemical properties
white to light brown granular powder
The Uses of (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide is used as a reactant in the synthesis of ketolides methyloxoerythromycins with antibacterial activity as highly potent against macrolide-resistant and susceptible respiratory pathogens.
The Uses of (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
Reactant for:
- Preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione
- Microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II
- Preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands
- Synthesis and antitumor agents
- Regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization
What are the applications of Application
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide is a Wittig ylide reagent
Purification Methods
Wash the crystals with Et2O, dry them in a vacuum and recrystallise them from CH2Cl2/dry Et2O to give prisms m 172-174o, which is raised to 191.5-193o on drying at 56o/0.5mm. [Cresp et al. J Chem Soc, Perkin Trans 1 37 1974.]
Properties of (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
Melting point: | 193-195 °C(lit.) |
storage temp. | Store below +30°C. |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Powder or Crystals |
color | White to light brown |
Water Solubility | Soluble in water (20°C). |
Sensitive | Hygroscopic |
CAS DataBase Reference | 52509-14-5(CAS DataBase Reference) |
Safety information for (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
InChIKey | FRHRVQQUICVJDG-UHFFFAOYSA-M |
Abamectin manufacturer
Dr. Silviu Pharmachem Pvt., Ltd.
1Y
Phone:+91-8390608382
Whatsapp: +91 8390608382
product: 52509-14-5 (1,3-Dioxolane-2-ylmethyl)triphenylphosphonium bromide 98%
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
BROMOMALEIC ANHYDRIDE
BROMOTRIS(TRIPHENYLPHOSPHINE)COPPER(I)&
Bromoacetaldehyde diethyl acetal
DIETHYL BROMOMALONATE
Bromo-PEG1-t-butyl ester
Diethyl bromodifluoromethanephosphonate
Sodium bromide
Chlorodimethylphenylsilane
You may like
-
52509-14-5 (1,3-Dioxolane-2-ylmethyl)triphenylphosphonium bromide 98%View Details
52509-14-5 -
(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide CAS 52509-14-5View Details
52509-14-5 -
(1,3-Dioxolan-2-yl)-methyltriphenylphosphonium bromide CAS 52509-14-5View Details
52509-14-5 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.