1,2-DIOCTANOYL-SN-GLYCEROL
Synonym(s):1,2-Dioctanoyl-sn-glycerol - CAS 60514-48-9 - Calbiochem;DG(8:0/8:0/0:0);DOG, PKC Activator IV
- CAS NO.：60514-48-9
- Empirical Formula: C19H36O5
- Molecular Weight: 344.49
- MDL number: MFCD00036835
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 1,2-DIOCTANOYL-SN-GLYCEROL?
Chemical properties
Off-White Solid
The Uses of 1,2-DIOCTANOYL-SN-GLYCEROL
1,2-Dioctanoyl-sn-glycerol is a cell permeable analog of the PKC-activating second messenger DAG. 1,2-Dioctanoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.[Cayman Chemical]
The Uses of 1,2-DIOCTANOYL-SN-GLYCEROL
Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells.
What are the applications of Application
1,2-Dioctanoyl-sn-glycerol is a cell-permeable analog of diacylglycerol and activator of protein kinase C (PKC).
Definition
ChEBI: 1,2-diacyl-sn-glycerol in which both the 1- and 2-acyl groups are specified as octanoyl.
Properties of 1,2-DIOCTANOYL-SN-GLYCEROL
| Boiling point: | 429.1±12.0 °C(Predicted) |
| Density | 0.992±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| form | oil |
| pka | 13.70±0.10(Predicted) |
| color | yellow |
| Stability: | Temperature Sensitive |
| CAS DataBase Reference | 60514-48-9(CAS DataBase Reference) |
Safety information for 1,2-DIOCTANOYL-SN-GLYCEROL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1,2-DIOCTANOYL-SN-GLYCEROL
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