1,2-DIOCTANOYL-SN-GLYCEROL

Synonym(s):1,2-Dioctanoyl-sn-glycerol - CAS 60514-48-9 - Calbiochem;DG(8:0/8:0/0:0);DOG, PKC Activator IV

CAS NO.：60514-48-9
Empirical Formula: C19H36O5
Molecular Weight: 344.49
MDL number: MFCD00036835
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 1,2-DIOCTANOYL-SN-GLYCEROL?

Chemical properties

Off-White Solid

The Uses of 1,2-DIOCTANOYL-SN-GLYCEROL

1,2-Dioctanoyl-sn-glycerol is a cell permeable analog of the PKC-activating second messenger DAG. 1,2-Dioctanoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.[Cayman Chemical]

The Uses of 1,2-DIOCTANOYL-SN-GLYCEROL

Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells.

What are the applications of Application

1,2-Dioctanoyl-sn-glycerol is a cell-permeable analog of diacylglycerol and activator of protein kinase C (PKC).

Definition

ChEBI: 1,2-diacyl-sn-glycerol in which both the 1- and 2-acyl groups are specified as octanoyl.

Properties of 1,2-DIOCTANOYL-SN-GLYCEROL

Boiling point:	429.1±12.0 °C(Predicted)
Density	0.992±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO: soluble
form	oil
pka	13.70±0.10(Predicted)
color	yellow
Stability:	Temperature Sensitive
CAS DataBase Reference	60514-48-9(CAS DataBase Reference)

Safety information for 1,2-DIOCTANOYL-SN-GLYCEROL

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.