1-Bromo-2-chloroethane

Synonym(s):Ethylene bromochloride;Ethylene chlorobromide

CAS NO.：107-04-0
Empirical Formula: C2H4BrCl
Molecular Weight: 143.41
MDL number: MFCD00000962
EINECS: 203-456-0
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 1-Bromo-2-chloroethane?

Chemical properties

Clear colorless to slightly yellow liquid

The Uses of 1-Bromo-2-chloroethane

1-Bromo-2-chloroethane was used in regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans. 1-Bromo-2-chloroethane is used as a solvent and as an intermediate for organic synthesis. It is used as a as fumigant.

Definition

ChEBI: A bromoalkane that is bromoethane substituted by a chloro group at position 2.

General Description

Clear colorless liquid with a sweet chloroform-like odor.

Air & Water Reactions

Slightly water soluble.

Reactivity Profile

1-Bromo-2-chloroethane is incompatible with strong bases, strong oxidizing agents and magnesium .

Fire Hazard

Literature sources indicate that 1-Bromo-2-chloroethane is nonflammable.

Purification Methods

Wash it with conc H2SO4, water, 10% Na2CO3 solution, and again with water, then dry with CaCl2 and fractionally distil before use. [Beilstein 1 H 89, 1 I 28, 1 II 61, 1 III 179, 1 IV 155.]

Properties of 1-Bromo-2-chloroethane

Melting point:	−18-−14 °C(lit.)
Boiling point:	106-107 °C(lit.)
Density	1.723 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4884(lit.)
Flash point:	104-107°C
storage temp.	Store below +30°C.
solubility	water: soluble
form	Liquid
color	Clear colorless to slightly yellow
Water Solubility	7 g/L (20 ºC)
Sensitive	Light Sensitive
BRN	605265
Dielectric constant	7.1399999999999997
CAS DataBase Reference	107-04-0(CAS DataBase Reference)
NIST Chemistry Reference	Ethane, 1-bromo-2-chloro-(107-04-0)
EPA Substance Registry System	1-Bromo-2-chloroethane (107-04-0)

Safety information for 1-Bromo-2-chloroethane

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H350:Carcinogenicity
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.