(+)-Dimethyl L-tartrate

Synonym(s):L-(+)-Tartaric acid dimethyl ester

CAS NO.：608-68-4
Empirical Formula: C6H10O6
Molecular Weight: 178.14
MDL number: MFCD00064437
EINECS: 210-166-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:00:57

What is (+)-Dimethyl L-tartrate?

Chemical properties

Colorless to light yellow liqui

The Uses of (+)-Dimethyl L-tartrate

(+)-Dimethyl L-tartrate is used as a starting reagent in the synthesis of (+)-Monomorine I, a pyrrolidine-based alkaloid that is a trail pheromone of the Pharaoh’s ant (Monomorium pharaonis).

The Uses of (+)-Dimethyl L-tartrate

(+)-Dimethyl L-tartrate can react with sulfur tetrafluoride to form dimethyl meso-2,3-difluorosuccinate.
It may be used in the synthesis of the following chiral ligands for use in asymmetric synthesis:

(2R, 3R)-1,4-dimethoxy-1,1,4,4-tetraphenyl-2,3-butanediol
(-)-(4S,5R)-4-(2-pyridyl)-5-(diphenylphosphino)methyl-2,2-dimethyl-1,3-dioxolane (PYDIPHOS)
(4R,5R)-α,α,α′,α′-2,2-hexaphenyl-4,5-dimethanol-1,3-dioxolane

Properties of (+)-Dimethyl L-tartrate

Melting point:	57-60 °C (dec.) (lit.)
Boiling point:	163 °C/23 mmHg (lit.)
alpha	21 º (c=10, H2O)
Density	1.238 g/mL at 25 °C (lit.)
refractive index	21 ° (C=2.5, H2O)
Flash point:	>230 °F
storage temp.	Inert atmosphere,Room Temperature
pka	11.44±0.20(Predicted)
form	Crystals
color	White
Specific Gravity	1.3046 (50/4℃)
optical activity	[α]22/D +21°, c = 2.5 in H2O
Water Solubility	Soluble in water.
BRN	1726256
CAS DataBase Reference	608-68-4(CAS DataBase Reference)
NIST Chemistry Reference	Butanedioic acid, 2,3-dihydroxy- [R-(R,R)]-, dimethyl ester(608-68-4)
EPA Substance Registry System	Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, dimethyl ester (608-68-4)