(+)-Anabasinehydrochloride

CAS NO.：53912-89-3
Empirical Formula: C10H14N2.HCl
Molecular Weight: 0
MDL number: MFCD01691578
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-30 15:45:59

What is (+)-Anabasinehydrochloride?

The Uses of (+)-Anabasinehydrochloride

(+)-Anabasine Hydrochloride is a hydrochloride analog of (S)-Anabasine (A637170), which is a nicotinic receptor agonist.

What are the applications of Application

(S)-1,2,3,4,5,6-Hexahydro-[2,3′]bipyridinyl hydrochloride is an AChR partial agonist

Biological Activity

High affinity neuronal nicotinic ACh receptor partial agonist (K i values are 0.058, 0.26 and 7.2 μ M for rat α 7, rat α 4 β 2 and fish skeletal muscle nAChRs respectively). Also stimulates Ca 2+ -dependent catecholamine release from rat adrenomedullary cells in vitro .

storage

Desiccate at RT

Properties of (+)-Anabasinehydrochloride

Melting point:	220-222 °C
Flash point:	9℃
storage temp.	Desiccate at RT
form	Powder
Water Solubility	Soluble to 100 mM in water

Safety information for (+)-Anabasinehydrochloride

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.