Pyridine hydrochloride
Synonym(s):Pyridinium chloride
- CAS NO.:628-13-7
- Empirical Formula: C5H5N.ClH
- Molecular Weight: 115.56
- MDL number: MFCD00012802
- EINECS: 211-027-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
![Pyridine hydrochloride Structural](https://img.chemicalbook.in/CAS/GIF/628-13-7.gif)
What is Pyridine hydrochloride?
Chemical properties
white to tan crystals
The Uses of Pyridine hydrochloride
Pyridine Hydrochloride is the hydrochloride salt of pyridine, a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niaci n and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.
The Uses of Pyridine hydrochloride
Pyridine Hydrochloride is the hydrochloride salt of pyridine, a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.
Preparation
Pyridine hydrochloride could be synthesized through the liquid-liquid synthesis method (pyridine and hydrochloric acid) and the gas-liquid synthesis method (pyridine and hydrogen chloride gas) respectively. The yield of the liquid-liquid synthesis method was 85% and the gas-liquid synthesis method was 92%.
Purification Methods
Crystallise the salt from CHCl3/EtOAc and wash it with Et2O. It is hygroscopic.[Beilstein 20 H 185, 20 I 57, 20 II 103, 20 III/IV 2230, 20/5 V 180.]
Properties of Pyridine hydrochloride
Melting point: | 145-147 °C(lit.) |
Boiling point: | 222-224 °C(lit.) |
Density | 1.1182 (rough estimate) |
refractive index | 1.5304 (estimate) |
Flash point: | 222-224°C |
storage temp. | Inert atmosphere,Room Temperature |
solubility | ethanol: soluble50mg/mL, clear, colorless to light yellow |
form | Crystals |
color | White to tan |
Water Solubility | 85 g/100 mL |
Sensitive | Hygroscopic |
BRN | 3615340 |
Stability: | Hygroscopic |
CAS DataBase Reference | 628-13-7(CAS DataBase Reference) |
EPA Substance Registry System | Pyridine hydrochloride (628-13-7) |
Safety information for Pyridine hydrochloride
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Pyridine hydrochloride
InChIKey | AOJFQRQNPXYVLM-UHFFFAOYSA-N |
New Products
1-Amino-1-cyclohexanecarboxylic acid Cycloleucine 6-Bromo-3-iodo-1-methyl-1H-indazole 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 7-Bromo-1H-indazole ELECTROLYTIC IRON POWDER 2-Methyl-2-phenylpropyl acetate 1-Aminocyclobutanecarboxylic acid 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride Decanonitrile tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate 4-Ethylbenzylamine Methyl 5-bromo-2-chloro-3-nitrobenzoate N-(5-Amino-2-methylphenyl)acetamide 2-Chloro-3-nitropyridine 5-Bromo-2,3-dimethoxypyridine methyl 6-chloro-2-(chloromethyl)nicotinate 2-methoxy-4-methyl-5-nitro pyridine 2-iodo-5-bromo pyridine 2-amino-4-methyl-5-nitro pyridine 5-Fluoro-2-Oxindole methyl L-alaninate hydrochloride diethyl L-glutamate hydrochloride Ethyl tosylcarbamateRelated products of tetrahydrofuran
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